Sentences with phrase «using radiotracers»

Richard Hargreaves, executive director of imaging at Merck Research Laboratories, says, «Nuclear imaging using radiotracers gives the opportunity to put your arms around proof - of - concept very early in a drug discovery and development program by focusing the selection of doses to study on those proven to deliver enough drug to the target therapeutic sites.»

The current method of identifying bone lesions is to use the radiotracer MDP with a SPECT scanner.

Our current multi-centre pivotal study has shown that in many patients, by using a radiotracer with a novel receptor - based mechanism, the SN can be reliably identified and removed for biopsy without having to undertake more extensive surgery.

Not exact matches

«With further validation, this radiotracer could also potentially be used to perform targeted biopsies for precise tissue analysis, which could lead to earlier, more appropriate treatment for prostate cancer patients.»

The scientists used Brookhaven's Cyclotron — a small accelerator dedicated to isotope production — to produce the nitrogen radiotracer, which was then introduced to the soil in a stream of air.

MBI uses small, semiconductor - based gamma cameras to image the breast following injection of a radiotracer that tumors absorb avidly.

Now, using a novel PET radiotracer called Neuroflux, a team of researchers from the Athinoula A. Martinos Center for Biomedical Imaging at Massachusetts General Hospital (MGH) and the MassGeneral Institute of Neurodegenerative Disease has found a way to quantify olfactory sensory neurons and thus improve measurements of olfactory health.

For the JCI study, the team applied the radiotracer to monitor olfactory sensory neuron population dynamics in a rodent model, using PET to measure its uptake across the animals» lifespan, including during age - related neurodegeneration.

«This result is better than bone scanning with MDP,» Chen notes, referring to the most common radiotracer used today.

Their discovery could aid in the synthesis of new «radiotracers» — chemical compounds that contain a radioactive form, or isotope, of an element — for use with a noninvasive, high - resolution 3 - D medical imaging technology known as PET (positron emission tomography) scanning.

These imaging scans use radioactive materials called radiopharmaceuticals or radiotracers.

Because the study used cognitive stress as a challenge, it was not confounded by potential group differences in stimulant - induced changes in cerebellar radiotracer delivery.

Positron emission tomography (PET) uses small amounts of radioactive materials called radiotracers, a special camera and a computer to help evaluate your organ and tissue functions.

Interestingly, an imaging study comparing DA increases using BPND and 4 - propyl -9-hydroxynaphthoxazine -LRB-[11C] PHNO)(radiotracer with > 20-fold higher affinity for D3 over D2 receptors, and presumably more sensitive to competition with endogenous DA)(63, 64) in response to a stressor in individuals at high risk for schizophrenia showed that those who abused marijuana had a blunted response, consistent with decreased DA signaling (22).

We estimated the DV for each voxel, which corresponds to the equilibrium measurement of the ratio of the radiotracer's tissue concentration to that of its plasma concentration using a graphical analysis technique for reversible systems (38).

A pioneer in the diagnostic uses of radiation and the development and testing of radiotracers in the early days of nuclear medicine, Robert N. Beck, professor emeritus in the Department of Radiology at the University of Chicago, died at the University of Chicago Medical Center on August 6, 2008, from myelodysplasia, a form of leukemia.

Measuring tau deposits using the novel radiotracer 18F - AV - 1451 (18F - T807), in conjunction with 11C - PiB to measure amyloid plaques and 18F - FDG to measure regional neurodegeneration, offers new insight into the neurodegenerative characteristics of Alzheimer's disease and shows that tau pathology may be an instrumental target for disease - modifying strategies.