Sentences with phrase «using sofosbuvir»

Using sofosbuvir - ledipasvir, which is sold as Harvoni, and is one several new drugs for hepatitis C, researchers compared the costs of treating patients at all stages of fibrosis, zero through four, with the cost of waiting until stages three or four, which is when some patients are usually treated.

Taylor's team of researchers examined Medicaid policies for hepatitis C virus treatment using sofosbuvir, more commonly known as Solvadi, and found that most should change policy to improve access to the treatment.

Not exact matches

The most common restrictions fall into three categories: 1) The level of fibrosis (i.e., scarring of the liver); 2) substance use and abstinence from alcohol / drug use together with toxicology screening; and 3) provider limitations, which limit the physicians allowed to prescribe sofosbuvir.

«In distinct contrast to the situation in the U.S., Australia's Pharmaceutical Benefits Advisory Committee (PBAC) recently recommended two highly effective sofosbuvir - based regimens for Pharmaceutical Benefits Scheme (PBS) listing, without drug use or disease stage - related restrictions,» said co-author and professor Greg Dore of the Kirby Institute.

In September 2017, the government of Malaysia issued a «government - use» license on sofosbuvir patents to allow 400,000 people living with hepatitis C in Malaysia to access generic HCV regimens in public hospitals.

«The results of the ION studies demonstrated highly satisfactory cure rates with a fixed dose combination of sofosbuvir / ledipasvir among patients with genotype 1 HCV infection without the use of either injectable interferon, which causes miserable flu - like symptoms, or ribavirin, an antiviral pill associated with a variety of troublesome side effects, including anemia and rash,» Professor Peck - Radosavljevic continued.

Data extracted included whether sofosbuvir was covered and coverage criteria based on liver disease stage; HIV coinfection; prescriber type; and drug / alcohol use.

During sofosbuvir's development, they had studied other drugs that inhibited different viral proteins and that might eliminate the need for continued use of interferon and ribavirin.

For this study, the team will test Sofosbuvir, a new drug, and Ribavirin, which is used in the treatment with interferon.

In subsequent tests using an immunodeficient mouse model infected by Zika, intravenous injections of sofosbuvir significantly reduced viral loads in blood serum compared to a placebo group.

In tests using human neural progenitor cells (NPCs)-- self - renewing, multipotent cells that generate neurons and other brain cell types — the scientists found that exposure to sofosbuvir not only rescued dying NPCs infected with the Zika virus, but restored gene expression linked to their antiviral response.

As part of a compassionate use program, 104 post-liver transplant patients with recurring HCV who had exhausted all treatment options and had poor clinical prognoses, received sofosbuvir (SOF) and ribavirin (RBV) with pegylated interferon (PEG) included at the physicians» discretion for up to 48 weeks.

The higher cure rate and lessened side - effects of treating patients with an all - oral combination of ledipasvir and sofosbuvir (LDV / SOF) results in greatly reduced absenteeism and improved workplace productivity that can translate into enormous benefit, according to the new economic model used by researchers at Inova Fairfax Medical Campus, VA..

Sofia will receive the 2016 Lasker - DeBakey Award on Sept. 23 along with Charles Rice, Ph.D., of Rockefeller University and Ralf Bartenschlager, Ph.D., of Heidelberg University, who were recognized for their work in developing systems essential to hepatitis C research, which Sofia used in developing the drug, sofosbuvir.

Today, with just 12 weeks of treatment with drug combinations that use Sofia's drug, sofosbuvir (Sovaldi ®) as the backbone of Harvoni ®, almost all those treated are cured.

Examples of DAAs, which come in pill form, are Olysio (simeprevir); Sovaldi (sofosbuvir), which is used in combination with Olysio; Daklinza (daclatasvir); and Harvoni (a combination of ledipasvir and sofosbuvir).