From correlation to causation: analysis of metabolomics data
using systems biology approaches — Antonio Rosato, Metabolomics
Borenstein and his team
use a systems biology approach and apply sophisticated computer modeling to understand the structure, function, and dynamics of the microbiome.
By
using a systems biology approach, researchers deliberately move away from the classic reductionist manner of looking at molecules in isolation to study biological systems in their entirety.
Extending cytokine / chemokine profiling platform (UNISI): Improvement of currently available services will be particularly focused on the optimisation of cytokine profiling for vaccine relevance
using a systems biology approach.
Her ongoing clinical training through the Institute for Functional Medicine
uses a systems biology approach when working with those who suffer from chronic and acute conditions to help them find their path to healing.
Functional medicine
uses a systems biology approach, which is a study of how our body's biological systems interact functionally with environment over time.
Not exact matches
A biologist, Schaal was among the first plant scientists to
use molecular
biology - based
approaches to understand evolutionary processes in plants and she has worked to advance understanding of plants» molecular
systems and population genetics.
His laboratory
uses a multidisciplinary
approach encompassing
systems biology, molecular pharmacology, biochemistry / proteomics, cell and structural
biology, and computation / bioinformatics.
There are ongoing studies which focus on the discovery of molecular biomarkers of the VSV - ZEBOV vaccine in healthy individuals
using omics - based technologies in combination with a
systems biology approach,» says Ali Harandi.
The Transcriptomics Core Facility supports a
systems biology approach in vaccine development focusing on the identification of transcriptomic correlates of vaccine immunogenicity and efficacy for a range of novel and licensed vaccines
using PBMC or whole - blood and BAL fluid samples.
It
uses cutting edge
approaches to understand entire
systems involved in complex
biology, from a cell to the central nervous
system.
Development of a gene expression assay in non-human primates: We will develop a novel sensitive assay for the characterisation of vaccination - related gene expression profiles in NHPs,
using an
approach that is fully harmonised with the
systems biology platform.
Using synthetic
biology approaches, I am engineering fluorescent organisms to monitor mechanical sensing
systems in response to pressure.
The research, published in the Proceedings of the National Academy of Sciences in September 2017,
uses a combination of real - world bacterial culture results and medical records from nursing home patients, and a computing
approach known as
systems biology.
«It validates the
approach of
using even very distant model
systems, such as the fly, to study human
biology.
An in vivo - vitro shuttle
system for the study of P. cynomolgi liver stages12 is being exploited to better understand hypnozoite
biology using molecular tools and genome - scale
approaches, which rely on the availability of a complete and well annotated P. cynomolgi reference genome sequence.
Integrated
systems biology approaches can identify gene regulatory networks, such as immune, stress and other regulatory responses, and link them with physiologic states.6 This bioinformatics
approach provides an unbiased view of the immune
system profile, and can be linked to changes in environmental conditions.7 These network
approaches, while often applied to identifying disease profiles, can be
used to identify salutary states as well, such as that which might result from intensive meditation.
Students receive training with a «
systems»
biology approach through courses, bench work, lab discussions and publications spanning a broad range of muscle -
biology questions
using studies at the level of single cells, tissues, animals and humans.
Using these
approaches in combination with genetics, molecular
biology and biochemistry, we are studying the molecular mechanisms underlying synaptic transmission and plasticity in mammalian central nervous
system.
Then for postdoctoral research I moved to Yale University, where I worked in a lab that looked at all kinds of different disease areas
using the
approaches of a field called chemical
biology, which is
using small molecules — chemicals — to probe biological
systems in the hopes of developing compounds that could be new drugs.
The ILRS PhD projects
use interdisciplinary
approaches, combining methods of microbiology, natural product chemistry, chemical ecology, bioinformatics and
systems biology to decipher complex biological mechanisms underlying microbial and biomolecular
It
uses cutting - edge
approaches to understand entire
systems involved in complex
biology, from a cell to the central nervous
system.
Using the replicative aging of the yeast Saccharomyces cerevisiae as an aging model, we will apply quantitative
systems biology approaches to investigate: 1.
One
approach uses systems biology strategies to better understand tumor progression and resistance to cancer therapeutics as well as to identify clinically useful biomarkers.
Specifically, the authors call for
systems biology approaches (
using large data sets and modeling to understand complex biological
systems) to fill critical knowledge gaps in understanding how Mycobacterium tuberculosis (Mtb) infection causes disease.