Sentences with phrase «using yeast models»

Eventually, using yeast models, the target of rapamycin (TOR) was identified, and the human counterpart was soon discovered — hence the name mammalian TOR, now given the catchy moniker — mTOR.

Using a yeast model of Parkinson's disease, Lee and his team discovered two of the compounds prevented the AS protein from clumping, effectively allowing the cells to grow normally.

Researchers used a yeast model to better understand the consequences of the mutations.

Not exact matches

The process of baking gluten free bread in a bread machine is the same, no matter which model you use: liquids first, then dry ingredients, then yeast.

Protein misfolding and aggregation had been identified as a major factor in mad cow disease, and research using yeasts as model organisms played a large role in those findings.

«Using yeast as a model organism, we studied the Tup1 protein, a negative regulator of gene expression,» says Biology Professor Emanuel Rosonina, adding, «This protein binds to some genes and blocks their expression, helping to ensure genes that shouldn't be turned on remain inactive.»

This group's achievement shows the possibility to clarify the mechanism of human tumor formation, especially the molecular mechanism responsible for in the initial stage of cell cancerization due to DNA damaged by radiation in the initial stage, by using the model of budding yeast, a primitive eukaryote.

A research group from the University of Seville has revealed the role that the protein Rrm3 plays in the repair of breaks that occur during the replication of DNA, by using the yeast Saccharomyces cerevisiae as a model organism.

Assistant Professor Kristin Baetz, who studies chromosome stability using yeast cells as a model, works with colleagues from different organizations, universities, programs, and disciplines.

So Virginia Cornish, a synthetic biologist at Columbia University, and her team set out to develop an alternative test with a long shelf life and no refrigeration using Saccharomyces cerevisiae, commonly known as baker's yeast, as their model fungus.

The researchers used proteins from baker's yeast — a model organism for the more complex systems found in animals.

Using a novel method they developed to map chromosome breaks in a model organism, the budding yeast, Wenyi Feng, Ph.D., of Upstate Medical University and her colleagues have discovered new information as to how and where chromosome fragile sites can occur in human DNA.

NASA will host a prelaunch panel discussion at 8 a.m. PDT Sept. 18, at the agency's Kennedy Space Center in Florida, featuring scientists and researchers who will discuss various science and research studies, including the four Ames - supported payloads to study model organism research using yeast, rodents, fruit flies and plants.

Using budding yeast Saccharomyces cerevisae, a frequently used laboratory model in aging research, Stowers scientists experimentally used heat and other forms of stress to induce misfolded proteins to clump together.

Using genetic models in a variety of organisms — yeast, nematodes, fruit flies, zebrafish — PLab aims to identify candidate treatment compounds for each disease, which can then be refined and taken to the clinic with partner companies.

Given the rapid succession of generations in yeast, we can use it as a model organism — and study the mechanisms of aneuploidy in much greater detail to find out whether we can derive from it new approaches for diagnosing and treating human diseases.»

Researchers at the Universities of Edinburgh and NYU Langone Medical Center have developed two types of molecular switch that work in yeast, a commonly used model organism.

Using yeast and fruit fly models, they discovered that only two of these DPRs were toxic, namely the glycine - arginine and proline - arginine DPRs.

Pol III was inhibited using a variety of genetic techniques across several different model organisms, from flies and worms to yeast.

They used yeast cells to model the disease, which allowed them to look at over 5,000 genes to map out which ones caused more or fewer cells to die.

In a second paper published in the same issue of Science, Lindquist and Outeiro teamed up with Paul Muchowski, an assistant professor in pharmacology at the University of Washington, to explore other uses of Outeiro's yeast model.

We modeled the secondary structure of rRNA using principles of compensatory base changes — where base - pairing in hairpin stem regions would be retained even if the sequence changes — and we found that there was a core structure that was conserved between Xenopus, yeast, and E. coli.

My lab at HPU studies membrane traffic during times of cellular stress using baker's yeast as a model system.

Chung and Khurana used the wealth of data from the yeast alpha - synuclein toxicity model to clue them in on key cellular processes that became perturbed as patient neurons aged in the dish.

The researchers focused on a well - known enzyme — called RNA polymerase II (RNAPII)-- and used the single - cellular yeast species S. cerevisiae as a model.

Using the replicative aging of the yeast Saccharomyces cerevisiae as an aging model, we will apply quantitative systems biology approaches to investigate: 1.