Vaccine adjuvants are substances that are added to vaccines to make them work better. They help boost our immune response, making the vaccine more effective in protecting us against diseases.
Full definition
Neal's work is focused on pre-clinical downselection and evaluation
of vaccine adjuvants for several emerging viral diseases.
They suggest that blockage of the IL - 28B receptor could offer a novel strategy to boost the antibody response to influenza vaccine and others, thus opening up a new avenue for developing
novel vaccine adjuvants and immunotherapeutic drugs.
Lastly, we need to move PfSEA -1-based vaccines into nonhuman primate challenge trials using human - use
approved vaccine adjuvants.
Since joining IDRI in 2007, Chris has played an integral role in developing, characterizing, and manufacturing
cGMP vaccine adjuvant formulations for a variety of infectious diseases, including leishmaniasis, malaria, tuberculosis, pandemic influenza, and amebiasis, resulting > 40 publications.
In other cases, clinicians may want to induce histamine release, thereby boosting the immune response, as in the case
of vaccine adjuvants, where an increased immune response may improve immunity.
In the area of Immunology our School is active in immunoregulation, immunomodulation, cell signalling in immunity and inflammation, immunoparasitology,
vaccine adjuvant research, innate immunity and Inflammation, and viral subversion of immunity.
But, biologists think that
vaccine adjuvants could be much better: The currently available licensed adjuvants are poor inducers of T helper cells and even worse at inciting killer T cells that clear viruses, as well as eradicate cancer cells.
Dynamics of APC recruitment at the site of injection following injection of vaccine adjuvants
Giuseppe's areas of expertise are immunology, infectious diseases, vaccines, vaccine adjuvants
Her laboratory is also studying the function of
the vaccine adjuvant alum, which dramatically biases immune responses to TH2 - type cells.
Vaccine adjuvants can cause serious chronic brain inflammation.