But Balin says that attempts to create
vaccines against strains of herpes and chlamydia found in the brains of Alzheimer's patients have proven difficult, and there's nothing currently on the horizon.
Not exact matches
A part of the research will include analyzing exactly why this year's flu
vaccine proved so ineffective
against the most common
strains circulating (the shot was just 25 % effective
against influenza A
strains).
Another caveat: It is still possible to contract the flu after getting a flu shot since the
vaccine you receive may not protect
against all
strains.
Preliminary estimates by the federal CDC show this year's version of the flu
vaccine is 36 percent effective
against all
strains of the flu, but just 25 percent effective
against the H3N2
strain causing most flu cases this winter.
The flu
vaccine can protect
against several
strains of the flu virus.
Based on preliminary effectiveness estimates, the CDC estimates that the flu
vaccine is approximately 25 % effective
against the H3N2
strain https://www.cdc.gov/mmwr/volumes/67/wr/mm6706a2.htm.
This year's
vaccine combines protection
against the H1N1 virus and several
strains expected to be most common during this flu season which runs through March.
These included the past two flu seasons in which
vaccines offered only limited protection
against the most widely circulating
strain of influenza A.
Are we close to being able to develop a universal flu
vaccine that would confer immunity
against all
strains of influenza?
Annual flu
vaccines are formulated to protect
against one type of influenza B and two
strains of influenza A, one H3N2
strain and one H1N1
strain.
In a preliminary study published in the April Journal of the American Medical Association, the researchers found that the
vaccine produced by this method protects
against the two
strains to which the subjects were exposed and most likely protects
against the third.
Each year, scientists create an influenza (flu)
vaccine that protects
against a few specific influenza
strains that researchers predict are going to be the most common during that year.
There is only a preliminary form of a
vaccine against H5N1 flu
strains, and even if there were a developed
vaccine, the virus might spread faster than public - health officials could get people inoculated.
The study, «The efficacy of the BCG
vaccine against newly emerging clinical
strains of Mycobacterium tuberculosis,» was published in the journal PLOS One in September.
Scientists may be able to create a «universal»
vaccine that can provide broad protection
against numerous influenza
strains, including those that could cause future pandemics.
Orme and his research team in Fort Collins investigated whether the existing
vaccine for TB, which goes by the acronym BCG (bacille Calmette - Guerin), worked equally well
against different clinical
strains of tuberculosis.
Dr Derek Gatherer of Lancaster University said: «Every year we have a round of flu vaccination, where we choose a recent
strain of flu as the
vaccine, hoping that it will protect
against next year's
strains.
«If you're going to test a new
vaccine in a specific place, you should look at the local
strains first and see if your
vaccines are effective
against the local
strains people are catching,» he said.
Seasonal influenza
vaccines are effective
against strains that are identified each spring in sentinel laboratories.
These antibodies protect
against certain
strains of influenza virus in the
vaccine, but may not provide thorough protection
against other
strains of flu that may be present.
«It was not known whether any of these
vaccines could provide protection against the new outbreak West African Makona strain of Ebola Zaire currently circulating in Guinea,» said John Eldridge, Chief Scientific Officer - Vaccines at Profectus Biosciences, Inc. «Our findings show that our candidate vaccines provided complete, single dose protection from a lethal amount of the Makona strain of Ebola virus
vaccines could provide protection
against the new outbreak West African Makona
strain of Ebola Zaire currently circulating in Guinea,» said John Eldridge, Chief Scientific Officer -
Vaccines at Profectus Biosciences, Inc. «Our findings show that our candidate vaccines provided complete, single dose protection from a lethal amount of the Makona strain of Ebola virus
Vaccines at Profectus Biosciences, Inc. «Our findings show that our candidate
vaccines provided complete, single dose protection from a lethal amount of the Makona strain of Ebola virus
vaccines provided complete, single dose protection from a lethal amount of the Makona
strain of Ebola virus.»
An interdisciplinary team from The University of Texas Medical Branch at Galveston and Profectus BioSciences, Inc. has developed a quick - acting
vaccine that is both safe and effective with a single dose
against the Ebola
strain that killed thousands of people in West Africa last year.
VaxInnate is testing a universal flu
vaccine that would work
against all
strains of the disease by using a Toll - like receptor (TLR) technology platform.
Previous infection with one serotype of dengue, or protection
against just one serotype, can lead to more severe disease if a person contracts other serotypes, so it's vital that
vaccines are available that specifically target all four
strains.
The
vaccine was less effective
against the B
strain (where a boost in titers was registered in more than 62 percent of participants) and H1N1 (where the boost was seen in more than 57 percent).
Understanding what combination of mutations could transform H5N1 into a human pandemic virus gives epidemiologists a leg up on preparing countermeasures; they can, for example, test existing
vaccines against the new
strain.
One reason
vaccines using weakened flu virus are not used in the elderly is that they have been exposed to many
strains of flu virus over the years and have more antibodies in the nasal tract, which can inhibit the weakened flu virus from infecting and stimulating the immune response necessary to protect
against the virus.
The
vaccine protected mice
against infection from
strains of H1N1 that the mice had never been exposed to.
The FDA approved Merck's Gardasil
vaccine in 2006, after clinical trials showed that it protects
against four
strains of human papillomavirus (HPV), which together cause about 70 percent of cervical cancers and 90 percent of genital warts.
Back to the future: Immunization with M - 001 prior to trivalent influenza
vaccine in 2011/12 enhanced protective immune responses
against 2014/15 epidemic
strain.
None of the available swine flu
vaccines can protect
against all these
strains.
However, researchers are working to develop universal
vaccines that could protect
against multiple flu
strains without needing to be updated.
Vaccines against the new
strain were developed and rolled out across the world from September to December 2009.
The swine vaccinated in Van Reeth's study also had increased immunity
against variant
strains that were not included in the
vaccine.
Professor Ajit Lalvani from the National Heart and Lung Institute at Imperial College London, who led the study, said: «New
strains of flu are continuously emerging, some of which are deadly, and so the Holy Grail is to create a universal
vaccine that would be effective
against all
strains of flu.»
«We wanted to test our
vaccine against H5N1 from Indonesia to see what the breadth of our antibody response would be
against that
strain,» Smith says.
«Single dose Ebola
vaccine is safe, effective in monkeys
against outbreak
strain: VSV - EBOV appears to trigger innate, adaptive immunity.»
National Institutes of Health (NIH) scientists report that a single dose of an experimental Ebola virus (EBOV)
vaccine completely protects cynomolgus macaques
against the current EBOV outbreak
strain, EBOV - Makona, when given at least seven days before exposure, and partially protects them if given three days prior.
Besser said officials were already taking preliminary steps toward manufacturing a
vaccine against the influenza
strain responsible for swine flu.
The researchers, led by Ram Sasisekharan, the Alfred H. Caspary Professor of Biological Engineering at MIT, also found that current flu
vaccines might not offer protection
against these
strains.
This means that when an unexpected flu
strain appears, such as the 2009 pandemic - causing H1N1 virus, there is no way to rapidly produce a
vaccine against it.
One of the
vaccines, which is based on a recombinant vesicular stomatitis virus expressing the glycoprotein of the Zaire
strain of the Ebola virus (VSV - ZEBOV), was recently shown to be extremely effective with 100 per cent efficacy
against the lethal Ebola virus disease in WHO - funded studies carried out in Guinea and Sierra Leone.
As a final confirmation of the compound's potential to stop a virus from spreading, they tested it
against an actual virus: the nonpathogenic
vaccine strain of the Junin virus.
Researchers around the world, including at the University of Rochester Medical Center (URMC), are pursuing a «universal» flu
vaccine, one that would protect
against most or all seasonal and pandemic
strains of the flu virus.
There are currently no
vaccines or drugs approved for human use and no post-exposure treatment that has completely protected nonhuman primates
against MARV - Angola, the most deadly Marburg viral
strain, with a mortality rate of up to 90 percent.
The most dangerous experiments involve
strains that are unfamiliar to our immune systems; neither our natural defenses nor existing
vaccines can protect us
against them.
The affordable
vaccine will at first protect
against just a single
strain of HPV that accountsfor 50 percent of cervical cancer.
The
vaccine protects
against four common
strains of the virus, considered the most common sexually transmitted disease in the United States.
Chicken farmers in Australia were using two live
vaccines, both made from Australian viral
strains,
against a poultry disease called infectious laryngotracheitis (ILT).
GlaxoSmithKline has developed a similar
vaccine that protects
against the two cancer - provoking
strains.