Not exact matches
In fact, even though they get
more vaccines now and are protected against
more vaccine - preventable diseases, kids actually get far fewer
antigens with each
vaccine than ever before.
Recombinant
vaccines rely on one or
more antigens — proteins associated with the target bacterium — that boost an immune response; in this case Mycobacterium tuberculosis, which causes TB.
The Cancer
Vaccine Collaborative is working on treatments that target multiple cancer
antigens, which should trigger a
more aggressive immune response and increase the odds of defeating tumors.
Compared to a bolus injection containing the same drugs and
antigens (but no scaffold), the 3D
vaccine was
more effective at preventing tumor growth, with 90 % of mice receiving the 3D
vaccine still alive at 30 days compared with only 60 % of mice given the bolus injection.
They could potentially play a role in the event of a pandemic, in this case by «
antigen sparing», allowing efficacy with lower doses of the influenza
antigen — thereby allowing faster production of
more doses of the
vaccine as early as possible in the pandemic.
These are
more specific therapies such as monoclonal antibodies and cancer
vaccines, which target specific tumor
antigens.
The department has developed and produced 15 different formulations for early clinical trials (e.g.
vaccine antigens produced by heterologous expression) and has conducted
more than 20 clinical trials as sponsor.
Overall, this study both identifies specific
antigen combinations for high - priority clinical testing and establishes a generalizable approach that is
more likely to produce effective
vaccines.
There is no evidence in Marek's disease that
vaccine breakthrough by
more virulent strains has anything to do with overcoming strain - specific immunity (e.g., epitope evolution); genetic and immunological comparisons of strains varying in virulence suggest that candidate virulence determinants are associated with host — cell interactions and viral replication, not
antigens [19].
So
vaccines contain either small amounts of inactivated
antigen or,
more recently, subunit
antigen particles that look like a virus to the body but can't really stimulate much of an immune response on their own.
Although young puppies and kittens exposed this frequently to
vaccine antigens may not demonstrate overt adverse effects, their relatively immature immune systems may be temporarily or
more permanently harmed.