Sentences with phrase «vaccine candidate antigen»

The overall aim of this project is to determine the functional significance of antibody targeted cellular and complement responses to a novel pediatric malaria vaccine candidate antigen, PfSEA - 1.

Set of basic assays to address a vaccine candidate antigens size, purity, quantity assembly status (multimers and / or aggregates), and integrity using analytical PAGE, SEC, FPLC / HPLC methods.

Not exact matches

Researchers plan to assess the new modified antigen against other candidates in advanced strep throat vaccine tests in nonhuman primates beginning later this year in Atlanta, Georgia, funded by the National Health and Medical Research Council of Australia.

«In addition, our method offers the potential to accelerate the development of new vaccines by allowing the efficient evaluation of candidate target antigens.»

Commercial arrays are not available for all biomarkers, so customised arrays for the analysis of vaccine candidates will be developed, featuring antigens for direct detection or antibodies for sandwich immunoassays (e.g. for cytokine detection).

This service will allow users to improve the compatibility and stability of their vaccine antigen with different mucosal adjuvants (from the HZI portfolio) and to define the optimal production methods to generate immunogenic vaccine candidates with optimised physicochemical stability (in vitro studies).

In vitro reconstitution of B cell receptor - antigen interactions to evaluate potential vaccine candidates.

These assays can be used to address the qualitative and quantitative properties of vaccine candidates by analysing (i) the vaccine candidate itself and (ii) antigen - specific immune responses in the serum of patients or immunised animals.

Formulation studies, including optimisation of adjuvanted vaccine candidates, stability studies, and the development of analytical methods to characterise antigen - adjuvant combinations

Of the seven tested antigens, one emerged as a strong candidate vaccine: AFF 1.

discovery of new vaccine targets by innovative approaches that allow the identification of non-classical vaccine antigens like non-protein antigens and subdominant epitopes and novel protein candidates

Other Ebola vaccine candidates use vector viruses to ferry a single Ebola protein, a surface antigen, to prime the immune system.

There is no evidence in Marek's disease that vaccine breakthrough by more virulent strains has anything to do with overcoming strain - specific immunity (e.g., epitope evolution); genetic and immunological comparisons of strains varying in virulence suggest that candidate virulence determinants are associated with host — cell interactions and viral replication, not antigens [19].

These events relate primarily to settlement of VaxGen's obligations under its lease of facilities in South San Francisco, and to the potential award of a procurement contract to Emergent BioSolutions (NYSE: EBS) by the U.S. Government for which VaxGen is eligible to receive milestone and royalty payments in connection with Emergent BioSolutions» May 2008 acquisition of VaxGen's recombinant protective antigen (rPA) anthrax vaccine product candidate and related technology.