«New Zika
vaccine candidate protects mice and monkeys with a single dose: Results from study highlight the promise of mRNA - based vaccines and therapies.»
The study showed that single shots of either
vaccine candidate protected mice against subsequent Zika challenge.
Not exact matches
The reliably high percentage of those who develop viremia following exposure to this challenge virus is another advantage — when most or all volunteers develop viremia or other signs of infection, clinical trials can enroll relatively small numbers of people but still achieve answers to such questions as whether a
candidate vaccine protects against infection, she noted.
«The findings from this trial are very encouraging to those of us who have spent many years working on
vaccine candidates to
protect against dengue, a disease that is a significant burden in much of the world and is now endemic in Puerto Rico,» said Stephen Whitehead, Ph.D., of NIH's National Institute of Allergy and Infectious Diseases (NIAID).
In 2009, a
vaccine candidate studied in a trial of over 16,000 individuals in Thailand was the first to modestly
protect against HIV infection.