Sentences with phrase «vaccine candidates from»

Picking vaccine candidates from the entire repertoire of genes for an organism «will probably be the only approach used to find vaccines in the future, because the technique is so powerful and so fast,» says Rappuoli.

Nanotheraputics for Antibiotic Resistent Emerging Bacterial pathogens (NAREB) European Research Infrastructures for Poverty Related Diseases (EURIPED) Biomarkers for enhanced vaccines immunosafety (BioVacSafe) European network of vaccine research and development TRANSVAC Advancing novel and promising TB vaccine candidates from discovery to preclinical and early clinical development (TBVAC2020)

Not exact matches

And by winter several more vaccine candidates that employ various forms of the virus are slated for human testing, supported by funds from the NIH.

«It was not known whether any of these vaccines could provide protection against the new outbreak West African Makona strain of Ebola Zaire currently circulating in Guinea,» said John Eldridge, Chief Scientific Officer - Vaccines at Profectus Biosciences, Inc. «Our findings show that our candidate vaccines provided complete, single dose protection from a lethal amount of the Makona strain of Ebola virusvaccines could provide protection against the new outbreak West African Makona strain of Ebola Zaire currently circulating in Guinea,» said John Eldridge, Chief Scientific Officer - Vaccines at Profectus Biosciences, Inc. «Our findings show that our candidate vaccines provided complete, single dose protection from a lethal amount of the Makona strain of Ebola virusVaccines at Profectus Biosciences, Inc. «Our findings show that our candidate vaccines provided complete, single dose protection from a lethal amount of the Makona strain of Ebola virusvaccines provided complete, single dose protection from a lethal amount of the Makona strain of Ebola virus.»

Gary Nabel, a molecular virologist with the University of Michigan Medical Center in Ann Arbor, and Anthony Sanchez, a virologist at the U.S. Centers for Disease Control and Prevention (CDC) in Atlanta, created their candidate vaccine from snippets of the Ebola virus's DNA.

The rVSV - ZEBOV vaccine candidate was initially engineered by scientists from the Public Health Agency of Canada and was licensed to a subsidiary of NewLink Genetics Corporation.

The new candidate vaccine contains mRNAs encoding two key proteins from a Zika virus strain isolated in a 2013 outbreak.

A single immunization with the vaccine candidate produced strong immune responses and prevented the virus from infecting mice at all.

«New Zika vaccine candidate protects mice and monkeys with a single dose: Results from study highlight the promise of mRNA - based vaccines and therapies.»

«[T] he visit also comes as the White House awaits action from Congress on a nearly $ 6.2 billion emergency appropriations request to continue fighting [Ebola] in West Africa and to move candidate vaccines through clinical trials.

The data obtained from this study provide a basis for more rapid, cost - effective clinical trials to evaluate new influenza drugs or to determine the efficacy of candidate vaccines for both seasonal and pandemic influenza.

«The findings from this trial are very encouraging to those of us who have spent many years working on vaccine candidates to protect against dengue, a disease that is a significant burden in much of the world and is now endemic in Puerto Rico,» said Stephen Whitehead, Ph.D., of NIH's National Institute of Allergy and Infectious Diseases (NIAID).

The candidate vaccine is made from a mixture of four live, weakened (attenuated) viruses targeted to each of the four serotypes.

Vaccine research will also benefit immediately from the discovery, since scientists can already now test the effectiveness of different vaccine candidates at preventing PfEMP1 from bindinVaccine research will also benefit immediately from the discovery, since scientists can already now test the effectiveness of different vaccine candidates at preventing PfEMP1 from bindinvaccine candidates at preventing PfEMP1 from binding ECPR.

The Dartmouth candidate, DAR - 901, is an inactivated vaccine made from a non-pathogenic bacterium that is genetically related to Mycobacterium tuberculosis, the cause of human tuberculosis.

The protein fragment of the vaccine candidate comes from gp120, a protein that covers HIV like a protective envelope.

Injecting rabbits with a vaccine candidate that contained the protein fragment without the sugar group resulted in antibodies that primarily bound to gp120 from only one HIV strain.

In clinical trials, several candidate H7N9 pandemic influenza vaccines made from inactivated viruses have been shown to be safe and to generate an immune response.

DEFENSE Vaccine candidates developed from DNA and proteins of the MERS virus (above, yellow) produced protective immune proteins and reduced lung damage in monkeys six days after infection.

«Our findings support PfSEA - 1 as a potential vaccine candidate, and we are confident that by partnering with our colleagues at the National Institutes of Health and other researchers focused on vaccines to prevent the parasites from entering red blood cells, we can approach the parasite from all angles, which could help us develop a truly effective vaccine to prevent this infectious disease that kills millions of children every year.»

Metabolomic profiling of vaccine candidates by SB measurement (LU): LU will analyse metabolic pathways based on samples from the above tasks and will extend the analyses to other project samples as well.

This service will allow users to improve the compatibility and stability of their vaccine antigen with different mucosal adjuvants (from the HZI portfolio) and to define the optimal production methods to generate immunogenic vaccine candidates with optimised physicochemical stability (in vitro studies).

Currently IDOBRU imports 66 Brucella vaccines from the Vaccine Ontology (VO; http://www.violinet.org/vaccineontology [21], including four licensed animal Brucella vaccines and 62 Brucella vaccine candidates that have been proven effective in laboratory animal modelVaccine Ontology (VO; http://www.violinet.org/vaccineontology [21], including four licensed animal Brucella vaccines and 62 Brucella vaccine candidates that have been proven effective in laboratory animal modelvaccine candidates that have been proven effective in laboratory animal models [33].

Presentations will include new data from Aeras's advancing portfolio of TB vaccines, including data from four clinical - stage candidates.

Results from the sporozoite stage vaccine look promising, the blood - stage candidate showed to be safe but will require further development, the transmission blocking candidate showed to be safe and immunogenic and the pre-erythrocytic candidate showed efficacy in UK adults.

Dr. Leo Stamatatos, an immunologist in Fred Hutch's Vaccine and Infectious Disease Division, has received funding from the National Institutes of Health to begin manufacturing an HIV vaccine candidate designed to stimulate the production of broadly neutralizing antibodies and to test the experimental vaccine in human clinical Vaccine and Infectious Disease Division, has received funding from the National Institutes of Health to begin manufacturing an HIV vaccine candidate designed to stimulate the production of broadly neutralizing antibodies and to test the experimental vaccine in human clinical vaccine candidate designed to stimulate the production of broadly neutralizing antibodies and to test the experimental vaccine in human clinical vaccine in human clinical trials.

In addition to finding vaccine candidates, «the most striking feature of N. meningitidis from a genome perspective is that there are more contingency genes than any other bacterium or organism studied so far,» says Hervé Tettelin, leader of the N. meningitidis sequencing project at TIGR.

His work centers on new immunomodulatory agents and formulations, as well as the process development necessary to take vaccines and therapeutic candidates from the lab to the clinic.

Results from the first Ebola vaccine clinical trial conducted in Africa (in 2009 - 2010) reveal a vaccine candidate produces the same immune response seen in the United States in an African setting.

As part of this upcoming study, some Ugandan volunteers from the 2009 DNA study will receive a boost, or additional injection, with the new vaccine candidate to explore a more long lasting effect of vaccination.

WCBS 880 AM — A «Promising Lead» in Fight Against Pancreatic Cancer - April 4, 2012 Early results from a clinical trial at CINJ show stable disease in pancreatic cancer for certain candidates following vaccine treatment.

Results from an initial study combining a microbicide candidate and experimental vaccine are promising enough to at least keep Imperial College virologist Robin Shattock coming back for more in pursuing what could be a novel move in preventing HIV infection.

Jeff Currier presented data from a Phase I study of a vaccine candidate that was developed by MHRP.

Under the terms of the sale of its assets and rights relating to its anthrax vaccine product candidate and related technology to Emergent BioSolutions Inc, (Emergent), Emergent may be obligated to pay VXGN up to an additional $ 7M in milestone payments, plus specified percentages of future net sales for 12.5 years beginning from the first commercial sale.

«Most vaccine candidates for malaria have worked by trying to prevent parasites from entering red blood cells,» said Dr Jonathan Kurtis of Rhode Island Hospital, the team's spokesman.