Sentences with phrase «vaccine dose group»

At all post-immunization time points, mean log antibody levels (µg / mL) were significantly higher in the malaria vaccine groups compared to the rabies vaccine group (t - test p - values < 0.0001 at all post-immunization time points for each malaria vaccine dose group compared to rabies vaccine group).

All doses of the malaria vaccine induced similar high levels of antibodies, with overlapping 95 % confidence intervals among the 3 malaria vaccine dose groups at all time points.

Not exact matches

For some vaccines, like tetanus, «the same dose is given to a 2 - month - old infant and an NFL football player,» says John Grabenstein, senior medical director for adult vaccines at Merck, who also sat on the working group and voted in favor of the recommendation this afternoon.

The group that received the high dose vaccine had a 19.7 percent hospital admission rate versus 20.9 percent in admission for those who received the standard dose vaccine.

The nursing homes in the study were randomly assigned to one of two groups as a care standard for influenza prevention, with either the regular dose of the influenza vaccine or the high dose vaccine as the care standard for their residents age 65 and older.

Whether the higher dose becomes the preferred procedure for nursing homes would be determined by the Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts that develop recommendations on use of vaccines in the civilian population.

Members of the other group received an HPV vaccine - specific brochure, plus telephone calls to parents who declined, and reminder calls to patients overdue for the second and third doses of the vaccine.

«Using an approved flu vaccine in a novel dosing schedule yielded promising results for a group patients at high risk for infection,» Branagan said.

Tested in a U.S. - sponsored trial that involved more than 16,000 volunteers in Thailand, the vaccine was administered in six injected doses starting in 2006 to half of the group, and the other half received a placebo.

As part of the study, groups of 18 to 20 female mice were vaccinated with one of the vaccines or a placebo, and some animals received a second dose of the same vaccine or placebo a month later.

Preliminary evidence suggested that the vaccine wards off disease; none of the patients who received the vaccine developed influenza in the winter after they were vaccinated, compared to two in a group who received a lower dose, and seven in the placebo group, the team reports today in the Journal of the American Medical Association.

The best immune response was shown in a group of nine test persons who received the highest dose of the vaccine three times at four - week intervals.

The PneumoADIP anticipates that a few so - called early adopter countries would realistically order one million to three million doses of vaccine in the next three years at a range of (donor - subsidized) prices that manufacturers might accept, observes Angeline Nanni, the group's director of vaccine supply and finance.

Among the latter group, about 46 out of every thousand were hospitalized per year of observation; among those who had received a dose of anthrax vaccine, that number was only 25 — a statistically significant difference.

The results showed that children in the educational text message reminder group were significantly more likely to receive a second dose of influenza vaccine (72.7 %) than both those in the conventional text message reminder group (66.7 %) and written reminder - only group (57.1 %).

The new backbone could help streamline annual vaccine production, which could be especially relevant during a pandemic, notes Kawaoka's group, when the sudden emergence of novel strains forces companies to rapidly make millions of doses of a new vaccine.

The live attenuated vaccine primer created strong immune memory in both age groups, regardless of whether volunteers received one or two doses.

The vaccine, developed and tested by researchers from the National Institutes of Health and other groups, was administered in multiple doses intravenously.

Influenza remains a major health problem in the United States, resulting each year in an estimated 36,000 deaths and 200,000 hospitalizations.4 Those who have been shown to be at high risk for the complications of influenza infection are children 6 to 23 months of age; healthy persons 65 years of age or older; adults and children with chronic diseases, including asthma, heart and lung disease, and diabetes; residents of nursing homes and other long - term care facilities; and pregnant women.4 It is for this reason that the Centers for Disease Control and Prevention (CDC) has recommended that these groups, together with health care workers and others with direct patient - care responsibilities, should be given priority for influenza vaccination this season in the face of the current shortage.1 Other high - priority groups include children and teenagers 6 months to 18 years of age whose underlying medical condition requires the daily use of aspirin and household members and out - of - home caregivers of infants less than 6 months old.1 Hence, in the case of vaccine shortages resulting either from the unanticipated loss of expected supplies or from the emergence of greater - than - expected global influenza activity — such as pandemic influenza, which would prompt a greater demand for vaccination5 — the capability of extending existing vaccine supplies by using alternative routes of vaccination that would require smaller doses could have important public health implications.

In a comparison between the 781 participants who received the standard - dose trivalent inactivated vaccine and the 1885 who received the quadrivalent inactivated vaccine, the trivalent vaccine was not associated with significantly higher odds of influenza, either overall (odds ratio, 1.2; 95 % CI, 0.8 to 1.7) or according to age group (Figure 3).

According to Col Jerome Kim, Walter Reed Army Institute of Research, US, who was also part of the lead group for the study, apart from the current four doses of vaccines that were given to subjects in the phase III clinical trials in Thailand, they are planning to give a booster does after six months to increase the strength of the vaccine.

[5] Of the remainder, only three were serious adverse events, none of which were judged by the investigators to be unexpected or related to therapy: all occurred in the low - rather than the high - dose vaccine group, and all were lower back or knee pains common in older adults.

The sample size of 15 in the 10 µg dose group and 30 each in the 25 µg and 50 µg dose groups was chosen to balance the need to detect any possible untoward reactions against the need to limit the number of volunteers exposed to an experimental vaccine for evaluation of safety.

Geometric mean titers for the highest dose of the DI vaccine were higher for those vaccine groups in the Balb / c mice than the C57BL / 6 mice but only the nonadjuvanted DI vaccine group was significantly higher (p = 0.008, Mann Whitney U).

Two groups of 12 subjects each were randomized to receive either a low (15 µg) or a high (75 µg) dose of the vaccine, one injection monthly for the first 4 months, and were monitored for a total of one year; 8 subjects serving as untreated controls and treated with best usual care.

22 Next, the CDC aggressively increased the dosing and expanded the target groups for the influenza vaccine, recommending a double dose for infants at both six and seven months, plus subsequent annual doses, and a dose for all pregnant women, no longer limited to the second and third trimesters.22 As of 2013, more than half of influenza vaccines were still preserved with thimerosal, 22 with the availability of non-thimerosal versions subject to supply - and - demand dynamics.

Since the second dose of the vaccine is typically administered three weeks after the first dose, the first dose should ideally be administered at least four weeks before the exposure to a group of at - risk dogs.