Sentences with phrase «vaccine effectiveness»

Both methods have been used to improve vaccine effectiveness in older adults and other high - risk groups.

The authors note that manufacturing strategies may also play a significant role in reduced vaccine effectiveness.

«This particular virus has lower vaccine effectiveness,» he said.

This finding has some practical implications for vaccination and could point the way to additives that could boost vaccine effectiveness in elderly humans.

It is using next - generation genetic sequencing to study egg - induced mutations in the hopes of identifying some that improve rather than reduce vaccine effectiveness.

Stacey Schultz - Cherry, Ph.D., and Erik Karlsson, Ph.D., find adjuvant fails to bolster flu vaccine effectiveness in new study looking at obesity.

However, variations in seasonal influenza vaccine effectiveness over the past decade have raised questions about their protective ability and whether other factors, such as antibodies to the NA protein on the flu virus, should be considered in designing the annual flu vaccine to improve its performance.

Immune history influences vaccine effectiveness, interacting with other potential problems arising from the manufacturing process

Recently published research suggests that mutations occurring in egg - prepared vaccines may have contributed to decreased vaccine effectiveness during the 2016 - 2017 influenza season in the United States and the 2017 flu season in Australia.

Researchers examined Tdap vaccine effectiveness among adolescents previously vaccinated with only DTaP vaccines within Kaiser Permanente Northern California following both the 2010 and 2014 whooping - cough outbreaks.

A study led by St. Jude Children's Research Hospital found that obese mice are not protected against influenza infections by vaccines that include adjuvants, raising concerns about vaccine effectiveness in obese humans who are known to be at an increased risk for severe flu.

Plausible vaccination scenarios with a durable vaccine, the researchers found, are clearly beneficial: such strategies would reduce annual dengue incidence by as much as 80 % within five years, and that annual vaccine effectiveness approaches 65 % by the end of the 20 - year forecast period.

«Studies should continue to compare vaccine effectiveness before and after sexual debut and by vaccine doses received and to explore the role of herd immunity,» added Perkins.

She says that the conventional practice of measuring vaccine effectiveness via blood tests probably began with mouse models used for immunotherapy research.

«Experience with other meningococcal vaccines has shown that waning of bactericidal antibody titres was associated with a decline in vaccine effectiveness following infant vaccination with serogroup C meningococcal conjugate vaccines,» writes Dr. Matthew Snape, Department of Pediatrics, University of Oxford and National Institute for Health Research Oxford Biomedical Research Centre, Oxford, UK, with coauthors.

He notes that the new study is especially relevant because it worked in mammalian cells, which ultimately are a better way to grow the virus than eggs: It's a faster production system and avoids mutations that occur when the virus adapts to chicken eggs, which can compromise vaccine effectiveness.

Against B / Victoria viruses, which were not included in the trivalent inactivated vaccine, we observed significantly higher vaccine effectiveness for the quadrivalent inactivated vaccine than for the trivalent vaccine (57 % [95 % CI, 36 to 71] vs. − 99 % [95 % CI, − 311 to 4]; P = 0.01 for the comparison).

An international team led by researchers at the Broad Institute of MIT and Harvard, the Harvard T.H. Chan School of Public Health and Fred Hutchinson Cancer Research Center uncovered the influence of genetic variation on vaccine effectiveness after applying cutting - edge DNA sequencing technology to almost 5,000 patient blood samples.

That means it doesn't closely resemble the H3N2 circulating among people, he explained, and these changes could be affecting vaccine effectiveness.

T α 1 itself has been shown to exhibit antibacterial and antifungal properties, suppress tumor growth, increase vaccine effectiveness, and protect against oxidative damage.

When the researchers directly compared vaccine coverage against vaccine effectiveness, coverage proved key in saving lives:

But a drop in vaccine effectiveness from 40 percent to 20 percent would lead to just 28,343 additional deaths, as long as vaccine coverage remained at 40 percent.

Unfortunately, during the time maternal antibodies are present, they inhibit vaccine effectiveness.

«Factors that may influence influenza vaccine effectiveness.»

A 2014 study used epidemiological data to show egg - based mutations are associated with low vaccine effectiveness in human populations.

«PittVax will continue collecting, analyzing and reporting on flu cases and flu vaccine effectiveness in the Pittsburgh region, helping guide flu immunization recommendations,» said senior author Richard K. Zimmerman, M.D., M.P.H., professor in Pitt School of Medicine's Department of Family Medicine and Pitt Graduate School of Public Health's Department of Behavioral and Community Health Sciences.

Flu vaccine effectiveness can vary widely from year to year since scientists essentially have to try and predict which strains will be most prevalent, but is generally found to reduce flu illness risk by 40 % to 60 %.

So when people question the scientific consensus on issues such as climate change, vaccine effectiveness or the safety of genetically modified organisms (SN: 2/6/16, p. 22), it's no...

So when people question the scientific consensus on issues such as climate change, vaccine effectiveness or the safety of genetically modified organisms (SN: 2/6/16, p. 22), it's no surprise that one of the first inclinations of journalists and scientists has been to think, hey, these doubters just don't know the facts.

The long - held approach to predicting seasonal influenza vaccine effectiveness may need to be revisited, new research suggests.

Differences in individuals» immune responses linked to flu vaccine effectiveness, the importance of resting phases in B cell development and research into whether pathogens cause type 1 diabetes.