Current debate in veterinary medicine concerning issues related to
vaccine efficacy and safety, as well as the duration of immunity induced by the currently available vaccines, underscores a compelling need for more objective and scientific data.
Not exact matches
If you dig
and read studies examining the actual
safety and efficacy data about the various
vaccines, it is clear that vaccination prevents the development of a strong natural immune system.
«It's important for us to finish what we started...
and to make sure we get the data, the
safety and efficacy that's necessary to support the approval
and licensure of therapeutics
and vaccines,» Disbrow said.
«I believe in the 21st century, the classic public health measures that are critical can be complemented by the addition of rapid diagnostics; by the development of
vaccines, assessment of
safety and efficacy and then deployment;
and by the development of drugs.
Q: Do you mean prominent vaccinologists who believe in the
safety and efficacy of today's
vaccines?
Intervention from wealthy non-scientists such as the philanthropist Mary Lasker drove even deeper investment into animal - based
vaccines despite growing evidence of their lack of
safety and efficacy.
«A successful
vaccine requires a fine balance between
efficacy and safety —
vaccines made from attenuated live viruses generally offer fast
and durable immunity, but sometimes with the trade - off of reduced
safety, whereas inactivated
and subunit viruses often provide enhanced
safety but may require several doses initially
and periodic boosters.
Human
safety trials for a
vaccine to jump - start immunity could begin later this year; larger
efficacy trials may be a year
and a half away.
1) Facilitate safe off - label use of existing
vaccines — Support collaboration between the zoological community
and conservationists in the field to determine the
safety as well as
efficacy of existing distemper
vaccines that could be, at a minimum, administered opportunistically to endangered wild carnivores whenever they are being handled (e.g. during radio - collaring exercises or when being translocated to mitigate human - wildlife conflict).
[NIAID Director Anthony] Fauci says $ 56 million of the total would go toward a larger
efficacy trial in Liberia, which would include both the NIAID / GSK [GlaxoSmithKline]
vaccine and another made by NewLink Genetics of Ames, Iowa (pending more data from ongoing
safety trials).»
So Pasteur, says Geison, had «not yet established the
safety and efficacy» of the
vaccine when he gave it to the boy — although Pasteur himself had previously said that «what is possible in a dog may not be so in a man».
At the meeting, GlaxoSmithKline (GSK) of Rixensart, Belgium, which has the
vaccine furthest in development, spelled out how it might scale up production in parallel with the
safety and efficacy trials now under way so that the product could be ready for wider distribution by April if warranted.
Discussions
and interventions need to begin in early in pregnancy for parents who are questioning
vaccine safety and efficacy.
Since there is no
vaccine or specific approved treatment for Ebola virus disease (EVD), there is a «moral obligation» to collect
and share all data generated, to understand the
safety and efficacy of any intervention,
and to evaluate promising interventions to inform future research, says Dr. Eleanor Fish, the senior author
and senior scientist in the Toronto General Hospital Research Institute (TGHRI).
SEATTLE, WA
and DURHAM, NC — The HIV
Vaccine Trials Network (HVTN)
and the HIV Prevention Trials Network (HPTN) today announced the initiation of HVTN 704 / HPTN 085, also known as Antibody Mediated Prevention (AMP) or the AMP Study, a Phase 2b clinical trial to evaluate the
safety and efficacy of VRC01, a broadly neutralizing monoclonal antibody (bnAb).
The HVTN is an international collaboration that conducts all phases of clinical trials, from evaluating experimental
vaccines for
safety and the ability to stimulate immune responses, to testing
vaccine efficacy.
The HVTN's mission is to fully characterize the
safety, immunogenicity,
and efficacy of HIV
vaccine candidates with the goal of developing a safe, effective
vaccine as rapidly as possible for prevention of HIV infections globally.
A new paper published in the Journal of Allergy
and Clinical Immunology has reported on a multicentre trial to test the
safety and clinical
efficacy of a new
vaccine against grass pollen allergy in patients with grass pollen — induced rhinitis
and controlled asthma.
The full paper that this statement is in response to can be found at: Niederberger et al. 2018
Safety and efficacy of immunotherapy with the recombinant B - cell epitope — based grass pollen
vaccine BM32.
The development track will begin with a Phase I trial to test the
vaccine regimen's
safety and immunogenicity
and depending on those study results, a larger
efficacy study will follow.
«Successful antagonists, following clinical trials for
safety and efficacy, could be incorporated into the seasonal
vaccine as a way of enhancing responses.
PD01A: Promising Animal
Efficacy; Initial Human
Safety and Hints of Disease Modification At the time of our last post on α - synuclein
vaccines, AFFiRiS had published several papers about the AFFITOME immnotherapy discovery platform [8 - 11]
and had even begun their first Phase I trial of PD01A, but had kept nearly silent on many of the most elementary aspects of the
vaccine.
Previously we reported the development of liposome - based
vaccines and their
efficacy and safety in preclinical mouse models for tauopathy.
He also oversees the design
and execution of GLP toxicity studies, a critical final step before IDRI's
vaccines can be tested for
safety and efficacy in humans.
We are currently investigating the role of various T - cell costimulatory pathways in regulating the humoral
and cellular responses to
and between DENV
and ZIKV,
and are defining the particular pathways that should be targeted to maximize
safety and efficacy of
vaccines.
The same year, the FDA approved the start of the first human clinical trial of this
vaccine that demonstrated its
safety and efficacy at inducing an immune response against the virus.
Within the framework of TRANSVAC2, the HZI will offer access in the form of pre-clinical studies in the murine system to assess the immunogenicity,
safety and efficacy of specific
vaccine formulations.
Picker explained that clinical trials are gearing up to test the
safety and efficacy of a human version of the
vaccine.
Within the framework of TRANSVAC2, the HZI will offer access in the form of pre-clinical studies in the murine system to assess the immunogenicity,
safety and efficacy of specific
vaccine formulations containing a mucosal adjuvant.
She began to question the
safety and efficacy of
vaccines after observing many patients with kidney failure after receiving vaccinations.
Introducing VANGUARD ® CIV H3N2 / H3N8, a bivalent canine flu
vaccine with demonstrated
safety and efficacy for protection against both highly contagious H3N2
and H3N8 strains of canine influenza virus (CIV).
To receive the conditional license, the
vaccine was shown to be safe in a field
safety study,
and a reasonable expectation of
efficacy was demonstrated.
There is a need to more fully evaluate the
safety and efficacy of combined
vaccines,
and the strains of viruses used, in young pups.
After all, the best way to help protect horses against EIV is to vaccinate before exposure to this highly contagious respiratory disease.8
And that's why horse owners can depend on the FLUVAC INNOVATOR vaccine line, because it helps offer demonstrated protection against EIV and is backed by the Zoetis commitment to continuously monitor and evaluate the efficacy and safety of its produc
And that's why horse owners can depend on the FLUVAC INNOVATOR
vaccine line, because it helps offer demonstrated protection against EIV
and is backed by the Zoetis commitment to continuously monitor and evaluate the efficacy and safety of its produc
and is backed by the Zoetis commitment to continuously monitor
and evaluate the efficacy and safety of its produc
and evaluate the
efficacy and safety of its produc
and safety of its products.
Non-structural protein 1 (NS1) truncated (NS1 - 126, NS1 - 99
and NS1 - 73) or deleted (DNS1) H3N8 canine influenza viruses (CIVs) were tested for their
safety, immunogenicity
and protection
efficacy as live - attenuated influenza
vaccines (LAIVs) against wild - type (WT) H3N8 CIV.
All
vaccines have to undergo rigorous
safety and efficacy testing before they are licensed for use in cats by regulatory authorities.
«It showcases our confidence in the
safety and efficacy of our equine FLUVAC INNOVATOR ® line of
vaccines with the MetaStim ® adjuvant.
Our specific
vaccines are chosen for
efficacy and safety.
A more pro-active approach is still needed to standardize
and individualize the production
and use of veterinary
vaccines in order to ensure their
safety and efficacy.
Coupled with the often heated
and sometimes emotional national discussions regarding the
safety and efficacy of
vaccines, you may wonder if it's worth vaccinating your pet at all.
Merck's website states about its H3N2
vaccine: «This
vaccine has a reasonable expectation of
efficacy and safety.»
What that means is that studies of the
vaccines are still in process, so we don't have any data about the
efficacy and safety of these shots.
The
vaccines we use come from several manufacturers
and have been carefully selected because of their demonstrated
safety and efficacy.
3:00 p.m. Balancing
Safety and Efficacy of
Vaccine Protocols... Walking the Veterinary Tight Rope — Dr. Brian Dorcey, Zoetis
One - bottle combination
vaccine for swine emphasizes
efficacy,
safety and convenience in either a one - or two - dose protocol
Each
vaccine is carefully selected by the veterinarian for
safety and efficacy.
Despite the high
efficacy and safety of pet
vaccines, rabies is the cause of death in 60,000 humans annually; most victims come from impoverished rural areas in Asia
and Africa where dogs are not routinely vaccinated for rabies.
Technical Update: Fostera PRRS
Vaccine for One - Day old Piglets: Respiratory
Efficacy, Duration of Immunity,
and Safety Research
Most
vaccines are actually labeled for use in animals older than 6 weeks, which means they went through formal testing to prove
efficacy and safety only in animals of this age or older.
We do not choose
vaccines based on price, but on
efficacy and safety data that we review regularly.