Cats are unique in their high susceptibility to tumors at
vaccine injection sites.
At around the same time, the American Veterinary Medical Association (AVMA) Vaccine - Associated Feline Sarcoma Task Force initiated several studies to find out why 160,000 cats each year in the USA develop terminal cancer at
their vaccine injection sites.3 The fact that cats can get vaccine - induced cancer has been acknowledged by veterinary bodies around the world, and even the British Government acknowledged it through its Working Group charged with the task of looking into canine and feline vaccines4 following pressure from Canine Health Concern.
«Reports of a sarcoma (a cancerous mass arising from bone, cartilage, fat or muscle) developing at the site of
vaccine injection sites in some animals have led to the suspicion of a link between the vaccine and a disposition in some animals to this type of reaction,» reports PetMD.
It can occur spontaneously in cats who have not received vaccines; however, an increased frequency of this type of tumor has been observed at
vaccine injection sites.
Did you hear about how sometimes certain vaccines can cause a cat to grow a cancer tumor at
the vaccine injection site?
«One to 10 cats out of every 10,000 vaccinated against infectious diseases develop cancer at
the vaccine injection site,» said Julie Levy, the Maddie's ® Professor of Shelter Medicine at the University of Florida College of Veterinary Medicine.
Not exact matches
If your baby was recently immunized, the
site of the
vaccine injection may be a bit sore, and his refusal to nurse could stem from the way he's positioned at the breast.
The overwhelming medical evidence finds that most
vaccine side effects among newborns and young children are mild — swelling, redness and a small, hard lump at the
site of the
injection — and typically pass within a couple of days.
The researchers report mild side effects, such as swelling around the
injection site and mild to moderate flu symptoms in some participants within a week of getting the
vaccine.
Finally, the HZI will help develop in vivo imaging technologies to characterize (i)
vaccine biodistribution and persistence, and (ii) cellular and molecular changes at the
injection site and in draining lymphoid tissues, helping to refine the use of animal models.
The P27A
vaccine candidate has a good safety profile, no serious adverse events were observed and the most frequent adverse event was pain at the
injection site.
Pain and / or swelling at the
injection site were experienced by most recipients of the malaria
vaccine.
Grade 3 local adverse events consisted mainly of
injection site swelling (Figure 2), which was reported in all study groups, but had a higher frequency in the 50 µg malaria
vaccine group.
Dynamics of APC recruitment at the
site of
injection following
injection of
vaccine adjuvants
While the Centers for Disease Control and Prevention states that you can not catch the flu from a
vaccine, it does note that minor side effects from the shot can include soreness at the
injection site, aches, and a low - grade fever — and that's in perfectly healthy people.
They were dying after suffering plenty of
vaccine reaction symptoms within days of their DPT shot, symptoms like high fever; sudden collapse; hours of persistent crying or high pitched screaming with arching of the back that can be a sign of brain inflammation; severe diarrhea; redness, swelling and pain at the
injection site and signs of seizures that too many pediatricians were blowing off as unimportant.
Most
vaccines cause little more than pain and swelling at the
injection site.
Veterinarians minimize risk by carefully selecting
vaccines on the basis of a pet's individual needs and by choosing appropriate
injection sites.
(WHAT YOU SHOULD KNOW ABOUT
VACCINE - ASSOCIATED FIBROSARCOMA)(Also called
Injection Site Sarcoma)
Short term reactions to the
vaccine can include coughing, sneezing or a stuffed up nose, similar to the disease itself, as well as swelling at the
injection site, nausea, vomiting or diarrhea.
When it comes to
vaccines, some cat owners are worried about
injection site tumors and bad reactions.
Most dogs never experience adverse reactions to their
vaccines, but please notify us right away if you notice any the following symptoms: facial swelling, hives, itching, sneezing, vomiting, diarrhoea, lethargy, difficulty breathing, pain at the
injection site, lethargy, collapse or seizures.
These include pain and stinging at the
injection site, swelling (inflammation of surrounding tissue) and vasculitis (inflammation of blood vessels) and are not caused by the antigen itself being administered but rather by the conditions surrounding its administration (for example, temperature of the
vaccine or inactive ingredients in the
vaccine).
Other feline
vaccine manufacturers may contain harmful adjuvants which can cause
injection site tumors.
There is a
vaccine available that is supposed to protect cats against contracting FIV, but the effectiveness is poorly supported by current research, and there is also a small risk of the cat developing sarcomas at the
injection site.
In addition, some
vaccines occasionally cause a firm swelling at the
injection site (most often rabies, but occasionally FeLV and others).
Any type of
vaccine has the potential to trigger an allergic reaction or inflammation at the
injection site.
The reason for these recommendations is the possibility of VAS (
Vaccine - Associated Sarcoma), which can occur at the
site of the
injection.
Vaccines generally have few side effects except for occasional discomfort at
injection site or short term sluggishness, but please call us immediately if you notice any of the following after a vaccination:
Feline Veterinary Emergency Assistance - Provides emergency financial assistance to feline guardians who are unable to afford veterinary services to save their companion with
Vaccine Associated Sarcoma (VAS), also referred to as
Injection Site Sarcoma (ISS).
In a recent study published in the Journal of the American Veterinary Medical Association (JAVMA), researchers detailed a case - control study conducted between 2005 and 2008 with a stated intent of comparing «associations between
vaccine types and other injectable drugs with development of
injection -
site sarcomas in cats.»
- Feline Leukemia (our
vaccine is considered lower risk for
injection site sarcomas) every 3 years if your cat goes outdoors, may not be necessary if your cat is indoors only
Adjuvants Role in Pathogenesis of FISS In 1993, an epidemiologic study involving 345 cats with fibrosarcoma provided evidence that vaccination with feline leukemia virus (FeLV) and rabies virus
vaccines could lead to tumorigenesis at the
injection site, particularly when vaccination was repeatedly administered at the same
site.6
- One year Rabies
vaccine OR three year Rabies
vaccine (both are PureVax
vaccines considered lower risk for
injection site sarcomas)
Several years ago, an «all - killed» combination
vaccine for dogs was marketed, but some users encountered minor problems with discoloration of the adjuvant and local reactions at the
injection site.
AAHA = American Animal Hospital Association; AVMA = American Veterinary Medical Association; FeLV = feline leukemia virus; FISS = feline
injection -
site sarcoma; VAFSTF =
Vaccine - Associated Feline Sarcoma Task Force
In August 2003, the Journal of Veterinary Medicine carried an Italian study which showed that dogs also develop
vaccine - induced cancers at their
injection sites.5 We already know that
vaccine -
site cancer is a possible sequel to human
vaccines, too, since the Salk polio
vaccine was said to carry a monkey retrovirus (from cultivating the
vaccine on monkey organs) that produces inheritable cancer.
Adjuvanted Feline leukemia
vaccine can cause
Injection Site Fibrosarcomas, a fatal type of cancer.
Vets became much more judicious in their use of the feline leukemia
vaccine in an effort to reduce the incidence of
injection site tumors.
Comparative
vaccine - specific and other injectable - specific risks of
injection site sarcomas in cats.
Common negative reactions dogs have to rabies
vaccines include soreness at the
site of
injection, a bump at the
site of
injection, hair loss at the
site of
injection, lethargy for 24 hours after the
injection, mild gastro - intestinal upset for 24 hours after the
injection, hives, and facial swelling.
It is postulated that the adjuvants in
vaccines can cause chronic inflammation which leads to cancer at the
injection sites.
Cats are prone to develop often fatal skin cancer at the
site of
vaccine injection.
European Advisory Board on Cat Diseases, Feline
injection -
site sarcoma: ABCD guidelines on prevention and management: «Non-adjuvanted, modified - live or recombinant
vaccines should be selected in preference to adjuvanted
vaccines.»
Several years ago, an «all - killed» combination
vaccine for dogs was marketed, but some users encountered minor problems with discoloration and local reactions at the
injection site, and the product was withdrawn.
Some
vaccines may create tumors at the
injection site.
About 0.5 - 6.5 cases / 10, 000 cats will develop this tumor at the
site of a past
vaccine injection.
Feline Veterinary Emergency Assistance — Provides emergency financial assistance to cat and kitten guardians who are unable to afford veterinary services to save their companion with
Vaccine Associated Sarcoma (VAS), also referred o as
Injection Site Sarcoma (ISS).
The most common side effects of
vaccines are lethargy and pain or swelling at the
injection site.
We utilize an inactivated, non-adjuvanted rabies
vaccine for cats because this
vaccine is less likely to stimulate an inflammatory response at the
site of the
injection that could, in rare cases, trigger the development of a potentially life - threatening fibrosarcoma tumor.