Sentences with phrase «vaccine platforms»

Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys.

He is particularly interested in genetic and host determinants of virus replication and how this knowledge can be applied towards the development of self - replicating RNA vaccine platforms for emerging infectious diseases.

«In less than a year, our group and others have demonstrated that multiple vaccine platforms can provide robust protection against Zika virus challenge in animal models.

WRAIR scientists and collaborators are moving rapidly to develop and test the Zika Purified Inactivated Virus (ZPIV) vaccine candidate because it builds on «a flavivirus vaccine platform WRAIR previously developed which has been proven to be safe, effective, and able to meet regulatory requirements of the U.S. FDA,» said Col. Stephen Thomas, an Army infectious diseases physician, vaccinologist, and the WRAIR Zika program lead.

Several additional clinical trials testing different vaccine platforms including inactivated virus, DNA, mRNA, virus vector, and synthetic peptide vaccines are ongoing.

De Silva and Metz were recently named to a global research consortium to tackle Zika, and they're using the same nanoparticle vaccine platform as they work to develop a Zika vaccine.

He joined IDRI's formulations team in 2017 to engineer materials with defined nanoscale properties that can enable rapid translation of emerging vaccine platforms from lab to clinic.

Trevor Mundel, president of global health at the Gates Foundation, talks to Scientific American editor - in - chief Mariette DiChristina about the Coalition for Epidemic Preparedness Innovations (CEPI) and the efforts to create vaccine platforms for rapid responses to epidemics.

VSV, an animal virus that primarily affects cattle, has been successfully tested as an experimental vaccine platform against several viruses.

Based on these findings, the authors suggest that the role of NA immunity should be considered when studying influenza susceptibility and that NA antigens should be considered in the design of future flu vaccine platforms.

Prior to joining IDRI, Neal worked as a research scientist for Immune Design Corporation (IDC), where he was a member of a team focused on design, generation, and testing of a novel viral vector vaccine platform.

The inactivated flavivirus vaccine platform was the same technology the Institute used to create its Japanese encephalitis vaccine, which was licensed in 2009.

A research article published in the journal Science has reported the efficacy of three different vaccine platforms against the Zika virus in rhesus macaque monkeys.

The nanoparticle vaccine platform can be safer to certain populations than vaccines that use either live or killed virus, he said.

Two Biotechs Earn Analyst's Top Pick Ranking Source: Streetwise Reports (3/19/18) Echelon Wealth Partners analyst Doug Loe sees blue sky potential for one company's newly approved HIV compound, while the vaccine platform of a second company earned it Top Pick status as well.

The perspective notes that once a vaccine platform is established, such as that for DNA or mRNA vaccines, potentially it can be applied to multiple pathogens, especially within virus classes or families.

«The Army was able to move so quickly in developing, manufacturing and testing a Zika vaccine because of its extensive experience with this vaccine platform and long standing investments in the understanding and mitigation of flaviviruses, like yellow fever, dating back to the founding of WRAIR,» said Dr. Kayvon Modjarrad, Zika program co-lead and associate director for Emerging Infectious Disease Threats at WRAIR's MHRP.

It is worth noting that although congenital ZIKV infection is a major public health concern, none of these vaccine platforms specifically target pregnant women.