By day 57, 92 percent
of vaccine recipients mounted strong antibody responses against Zika virus, with levels of virus - neutralizing antibodies in the blood exceeding the protective thresholds observed in prior animal models.
It renders the virus incapable of causing an infection but still provokes the immune response that will
protect vaccine recipients against future infections.
Many of the digital systems currently in operation or being set up include the possibility to record whole - of - life vaccination data, and some countries can
provide vaccine recipients the possibility to print their personal immunisation history.
At least 21 and 37, respectively, have developed nonfatal inflammation of the heart, called myopericarditis; three
other vaccine recipients suffered fatal heart attacks, which have not been definitively tied to vaccines.
One concern is the development of multiple sclerosis, which has been fuelled by social and news media reports of cases occurring after HPV vaccination, and an increasing number of case reports published in the medical literature
describing vaccine recipients who developed multiple sclerosis as well as other demyelinating diseases.
We used a comparator vaccine group of 25 to permit broad estimates of the incidence of local and general side effects and of immune responses
among vaccine recipients compared to controls.
As vaccine recipients, we usually think only of the ability of the vaccine to protect us against a specific disease, but here the effects on the whole population and on the influenza virus itself are being considered.
Defining how to safely replicate these attributes in HIV -
uninfected vaccine recipients may lead to better designed experimental vaccines to protect against HIV.
The highest platelet counts were reported in a 10 µg
malaria vaccine recipient, with values of 1,096 × 103 / µL on the day of the second immunization (prior to immunization) and 1,397 × 103 / µL a week after the second immunization.
After the team demonstrated the potential benefits to
vaccine recipients, public health, and the company, the project was selected to take the first steps toward implementation.
Five of the digital systems include automated reminders, which have the potential to automatically generate lists that identify under vaccinated populations, determine which vaccines are due or overdue, and generate reminders for providers and
vaccine recipients.
Even more promising, most of
the vaccine recipients continued to produce protective antibodies a year after receiving their last shot.
This strategy instructs
the vaccine recipient to produce the antigen in his / her own body so that the immune system can be activated and mount a rapid and potent response against malaria.