Collaborators are planning clinical testing of this HIV
vaccine regimen in healthy adults at research sites in the U.S., East Africa, South Africa, and Thailand.
The U.S. Military HIV Research Program (MHRP) at the Walter Reed Army Institute of Research (WRAIR) initiated a Phase 2 clinical trial to evaluate the safety and immunogenicity of a prime - boost Ebola
vaccine regimen in both healthy and HIV - infected volunteers.
Research Trials The HVTN also plans to test other HIV
vaccine regimens in Southern Africa in a parallel research track using multiple vaccine candidates.
Not exact matches
«We seek to make TB
vaccine regimens for infants and adolescents available and licensed
in the next seven to nine years,» according to Yasir Skeiky, chief scientific officer of Aeras.
A team led by Ron Dagan, a pediatric infectious disease specialist at Soroka University Medical Center
in Beer - Sheva, Israel, wanted to know if a new pneumococcal
vaccine based on tetanus toxoid would change infants» immune responses to the standard
regimen of
vaccines, including those for diphtheria, tetanus, pertussis (DTP), and Haemophilus influenzae type B, which protects against meningitis.
In its first test in humans, reported online October 4 in the New England Journal of Medicine, one vaccine based on DNA from the virus elicited an immune response, with 100 percent of participants developing antibodies after a three - dose regime
In its first test
in humans, reported online October 4 in the New England Journal of Medicine, one vaccine based on DNA from the virus elicited an immune response, with 100 percent of participants developing antibodies after a three - dose regime
in humans, reported online October 4
in the New England Journal of Medicine, one vaccine based on DNA from the virus elicited an immune response, with 100 percent of participants developing antibodies after a three - dose regime
in the New England Journal of Medicine, one
vaccine based on DNA from the virus elicited an immune response, with 100 percent of participants developing antibodies after a three - dose
regimen.
Recently, monkey studies testing
vaccine regimens different from those
in RV144 have supported the notion that enhancing protective antibody activity may increase
vaccine efficacy.
«Cholera
vaccine study
in Haiti suggests problems with current booster
regimen.»
«Flu evolves quickly and
in complex ways,» so this will help the World Health Organization (WHO) track and aim at the right strains with annual
vaccines, says co-author Derek Smith, a Cambridge epidemiologist and member of the WHO committee tasked with planning WHO's annual flu shot
regimen.
After initial approval of a new
vaccine, research often continues and involves the testing
in different populations and of different dosing
regimens.
A new study led by scientists at Beth Israel Deaconess Medical Center (BIDMC) shows that an HIV - 1
vaccine regimen, involving a viral vector boosted with a purified envelope protein, provided complete protection
in half of the vaccinated non-human primates (NHPs) against a series of six repeated challenges with simian immunodeficiency virus (SIV), a virus similar to HIV that infects NHPs.
An HIV - 1 version of the promising
vaccine regimen is now being evaluated
in an ongoing Phase 1 / 2a international clinical study.
Based on these pre-clinical data, the HIV - 1 version of this
vaccine regimen is now being evaluated
in an ongoing Phase 1 / 2a international clinical study sponsored by Crucell Holland B.V., one of the Janssen Pharmaceutical Companies of Johnson & Johnson.
«Novel HIV
vaccine regimen provides robust protection
in non-human primates.»
Though these particular
vaccine regimens are not intended for the clinic, the results suggest that effective
vaccines for MERS could be developed from the Spike protein, says study coauthor Barney Graham, a vaccinologist at the National Institute of Allergy and Infectious Diseases
in Bethesda, Md..
If the WHO grants an emergency use listing, this will accelerate the availability of Janssen's investigational
vaccine regimen to the international community
in the event another Ebola crisis occurs.»
In the HVTN 100 study, the design and schedule of the RV144
vaccine regimen have been altered to try to increase the magnitude and duration of
vaccine - elicited immune responses.
This experimental
vaccine regimen is based on the one tested
in the U.S. Military HIV Research Program - led RV144 clinical trial
in Thailand — the first study to demonstrate that a
vaccine can protect people from HIV infection.
In September, the team added to the
vaccine regimen a drug called Keytruda that supports the immune system's attack on tumors.
Results from an initial study to ensure that the RV144
vaccine regimen is safe and well - tolerated
in South African volunteers were reported at the 2014 HIV Research for Prevention (R4P) conference.
Improving the
Vaccine Regimen Researchers have discovered important clues about the immune responses that may have played a role
in protecting some volunteers
in RV144.
Follow - up clinical studies using modified
vaccine regimens and extra boosts are set to begin
in Southern Africa
in 2015.
The HIV
Vaccine Trial Network (HVTN) plans to conduct clinical trials in heterosexual adults that will evaluate a prime - boost vaccine regimen similar to that used in RV144 adjusted to target the most common subtype of HIV in the region (subt
Vaccine Trial Network (HVTN) plans to conduct clinical trials
in heterosexual adults that will evaluate a prime - boost
vaccine regimen similar to that used in RV144 adjusted to target the most common subtype of HIV in the region (subt
vaccine regimen similar to that used
in RV144 adjusted to target the most common subtype of HIV
in the region (subtype C).
• RV217 (ECHO): HIV - 1 Prevalence, Incidence, Cohort Retention, and Host Genetics and Viral Diversity
in High Risk Cohorts
in East Africa • Infectious Disease Surveillance (HIV, TB and Malaria) and Cohort Development Among Urban and Rural Communities • Karolinska Institute
vaccine study
in Tanzania testing a prime - boost HIV
vaccine regimen using unadjuvanted DNA
vaccines followed by a Modified Vaccinia Ankara (MVA), which was developed by MHRP and NIAID.
2017 — Began a new multi-site Phase 2 Ebola
vaccine study at MHRP sites
in Africa evaluating a prime - boost
regimen in both healthy and HIV - infected volunteers (Ad26.ZEBOV from J&J; MVA - BN - Filo from Bavarian Nordic)
At the first plenary session of AIDS
Vaccine 2011, which opened this morning in Bangkok, Thailand, researchers presented the results of a two - year - long effort to try to identify an immunological explanation for the modest 31 % efficacy afforded by the prime - boost vaccine regimen tested in the RV144 trial, the first to show any efficacy in protecting against HIV inf
Vaccine 2011, which opened this morning
in Bangkok, Thailand, researchers presented the results of a two - year - long effort to try to identify an immunological explanation for the modest 31 % efficacy afforded by the prime - boost
vaccine regimen tested in the RV144 trial, the first to show any efficacy in protecting against HIV inf
vaccine regimen tested
in the RV144 trial, the first to show any efficacy
in protecting against HIV infection.
The new Ad26 / MVA and Ad35 / Ad26 vector - based
vaccine regimens resulted
in over 80 % reduction
in the per - exposure probability of acquisition of infection against repetitive challenges of SIV, a virus similar to HIV that infects monkeys.
Vaccines were delivered by the intramuscular route
in a ChAd63 - MVA heterologous prime - boost
regimen using an 8 - week interval.
At the International AIDS Society conference
in Paris, scientists announced that
in an early - stage clinical trial, a new HIV
vaccine regimen generated antibody responses
in 100 percent of volunteers
in most arms of the study.
In addition, importers in consultation with their veterinarians can elect to include Bordetella or other vaccines in their dog's vaccination regimen before or after impor
In addition, importers
in consultation with their veterinarians can elect to include Bordetella or other vaccines in their dog's vaccination regimen before or after impor
in consultation with their veterinarians can elect to include Bordetella or other
vaccines in their dog's vaccination regimen before or after impor
in their dog's vaccination
regimen before or after import.
It would not be included
in most dogs» annual core
vaccine regimen; but, for high - risk animals it may be warranted.