Sentences with phrase «vaccine responses in»

This insight may help us improve vaccine responses in the elderly — a group at particular risk of diseases including influenza — by pre-treatment with anti-inflammatory agents.»

«There is a critical public health need to translate these findings to humans and understand vaccine response in this growing segment of the population,» Schultz - Cherry said.

Not exact matches

Communicable Childhood Diseases Antibody response to oral and parenteral vaccines are higher in the breastfed infant.

In some cases, the doctor will advise a blood test for your baby around two months after the vaccination to assess their body's response to a particular vaccine.

5Zika vaccine: Florida Gov. Rick Scott, who has been highly critical of the federal response to the outbreak of the Zika virus, used his emergency powers Thursday to direct $ 25 million in state money toward helping to develop a vaccine.

The University of California, Los Angeles — led group reported in this week's Science that they may have created the «Goldilocks» of flu vaccines — one that manages to trigger a very strong immune response without making infected animals sick.

«HIV - 1 viruses transmitted at birth are resistant to antibodies in mother's blood: New research supports creation of vaccine to boost mother's immune response to HIV - 1 before delivery.»

But during her 2008 presidential run, in response to an autism advocacy group's questions, she cited vaccines as one possible environmental cause of autism, despite widespread scientific agreement that vaccines don't cause autism.

When injected into the skin of six rhesus macaque monkeys, the vaccine prompted an immune response that blocked the proteins from popping up in the brain.

In the case of vaccines, that emotional response probably stems from many things, Mnookin says, including frustration with our lack of personalized health care, a general distrust of large corporations and of big pharma specifically, distrust that isn't necessarily misplaced.

People using the patch had a similar immune response to the flu vaccine as those who received a typical flu shot, researchers report online June 27 in the Lancet.

A new study shows pregnant women who get flu shots regularly have a weaker peak antibody response to the vaccine than women who don't get them regularly, though mothers and their babies in both groups were well - protected at the time of delivery.

But the Yemeni government, with the help of a Saudi - led coalition, is battling Shiite Houthi rebels backed by Iran and there were concerns over whether the vaccine could be used effectively as battles raged in parts of the country, and whether administering it might distract health workers from treating patients, a cornerstone of epidemic response.

It was meant to boost immune responses in infants already primed by the BCG vaccine.

Recombinant vaccines rely on one or more antigens — proteins associated with the target bacterium — that boost an immune response; in this case Mycobacterium tuberculosis, which causes TB.

Sex differences in immune response could have real consequences when it comes to vaccine choice, Upham says.

This is because of a vaccine stockpile set up in response to the cholera that struck Haiti after an earthquake in 2010 — cholera carried there, ironically, by Nepalese peacekeepers.

In 2003, the government approved use of an injectable vaccine only in response to outbreakIn 2003, the government approved use of an injectable vaccine only in response to outbreakin response to outbreaks.

An injection of synthesized rabies antibodies — or immunoglobulin — is administered to help patients combat the virus while their immune system creates antibodies in response to the vaccine.

«Our ability to control these reactions and use them to form a response to the vaccine will be critical in designing the next generation of vaccines,» Kemble says.

In response to the Ebola Zaire outbreak, several of these vaccines have been fast tracked for human use.

The vaccine relies on the rabies virus to deliver Ebola proteins that elicit an immune response in chimps, but it hasn't been tested in the field yet.

There he worked on anticancer vaccines, identifying drug targets, preparing vaccine formulations, and testing cellular responses in vaccinated patients.

«This particular vaccine approach didn't work, but there are lots of different vaccine approaches in testing that produce different immune responses,» Buchbinder says.

«Understanding the host response will be a critical area in vaccine research,» says George Kemble, vice president of research and development for MedImmune Vaccines, recently purchased by AstraZeneca.

This synthetic vaccine will hopefully trigger in recipients an antibody response that will help fight off any Zika virus it encounters.

Trevor Mundel, president of global health at the Gates Foundation, talks to Scientific American editor - in - chief Mariette DiChristina about the Coalition for Epidemic Preparedness Innovations (CEPI) and the efforts to create vaccine platforms for rapid responses to epidemics.

In collaboration with many researchers (graduate students, postdocs, and faculty elsewhere), we have examined the role of cross-immunity on the evolution and dynamics of influenza; the impact of behavioral changes, long periods of infectiousness, variable infectivity, co-infections, prostitution, social networks, and vaccine efficacy on HIV dynamics; the role of exogenous re-infection, variable progression rates, vaccination, public transportation, close and casual contacts on tuberculosis dynamics and control; the impact of life - history vector dynamics on dengue epidemics; and on the identification of time - response scales for epidemics of foot and mouth disease.

Essentially, he's looking for immune cells with barcodes that proliferate in individuals with a good response, as opposed to those in whom the vaccine is ineffective.

Understanding the body's immune response to a given vaccine could help make better and more effective vaccines in the future.

One reason vaccines using weakened flu virus are not used in the elderly is that they have been exposed to many strains of flu virus over the years and have more antibodies in the nasal tract, which can inhibit the weakened flu virus from infecting and stimulating the immune response necessary to protect against the virus.

But those vaccines are far from perfect: They don't always exactly match the viruses actually going around, and in some people, the shots fail to trigger a vigorous immune response.

A team led by Ron Dagan, a pediatric infectious disease specialist at Soroka University Medical Center in Beer - Sheva, Israel, wanted to know if a new pneumococcal vaccine based on tetanus toxoid would change infants» immune responses to the standard regimen of vaccines, including those for diphtheria, tetanus, pertussis (DTP), and Haemophilus influenzae type B, which protects against meningitis.

The company's vaccine approach in both cases is to use viruslike particles (VLPs) containing surface proteins that make the VLPs resemble a virus, thereby eliciting the proper immune response — even though the VLPs lack the genes needed to replicate themselves.

«These results imply that, of the options currently available utilizing adjuvants included in the national stockpile, based on the immune response data, AS03 should be considered a first - line adjuvant for strategies incorporating an inactivated H7N9 vaccine in adults,» the authors write.

Back to the future: Immunization with M - 001 prior to trivalent influenza vaccine in 2011/12 enhanced protective immune responses against 2014/15 epidemic strain.

Writing in February in Vaccine, the researchers reported that the stored serum of elderly volunteers who received the vaccine in 2011 showed an immune response to new strains of flu that were circulating three yearsVaccine, the researchers reported that the stored serum of elderly volunteers who received the vaccine in 2011 showed an immune response to new strains of flu that were circulating three yearsvaccine in 2011 showed an immune response to new strains of flu that were circulating three years later.

The ZPIV vaccine candidate was developed by WRAIR as part of the US Department of Defense response to the 2015 - 2016 outbreak of Zika virus in the Americas, and it was advanced to a Phase 1 trial in November 2016.

Working with the Tulane National Primate Center in Louisiana, Friedman and his group showed that the trivalent vaccine — given three times at monthly intervals — induced a strong immune response in macaque monkeys, whose immune system closely resembles the human version.

The personalized vaccine is made from patients» own immune cells, which are exposed in the laboratory to the contents of the patients» tumor cells, and then injected into the patients to initiate a wider immune response.

The vaccine also induced a sharp rise in CD4 T - cells, whose job is to mobilize the antibody response and other immune elements against viral infections.

In nearly all individuals immunized with the investigative vaccine, ZPIV produced neutralizing antibody responses at two or four weeks after the last dose.

«Personalized tumor vaccine shows promise in pilot trial: Vaccine against patients» own tumors triggers a broad response, and induced five - year remission in one patient with advanced ovarian cancer.vaccine shows promise in pilot trial: Vaccine against patients» own tumors triggers a broad response, and induced five - year remission in one patient with advanced ovarian cancer.Vaccine against patients» own tumors triggers a broad response, and induced five - year remission in one patient with advanced ovarian cancer.»

All studies showed the addition of the B strain improved the antibody response to that strain and didn't weaken the body's immune response to other flu strains in the vaccine.

With no head in place to hoard the immune response, the vaccine might coax the body to make enough stem - focused antibodies to protect against flu, the researchers hoped, regardless of the seasonal mutations occurring at the top.

In a phase 2 trial that included nearly 1,000 adults, the AS03 and MF59 adjuvants (a component that improves immune response of inactivated influenza vaccines) increased the immune responses to two doses of an inactivated H7N9 influenza vaccine, with AS03 - adjuvanted formulations inducing the highest amount of antibody response, according to a study in the July 21 issue of JAMIn a phase 2 trial that included nearly 1,000 adults, the AS03 and MF59 adjuvants (a component that improves immune response of inactivated influenza vaccines) increased the immune responses to two doses of an inactivated H7N9 influenza vaccine, with AS03 - adjuvanted formulations inducing the highest amount of antibody response, according to a study in the July 21 issue of JAMin the July 21 issue of JAMA.

Maternal immunization is one way to help protect them because the antibodies that the mom generates in response to the vaccine can be passed to her unborn child.

«We are pleased to have demonstrated such a potent and durable immune response to the vaccine,» said the study's lead author, Sita Awasthi, PhD, a research associate professor of Infectious Diseases at Penn. «If found effective in clinical trials, the vaccine will have a huge impact on reducing the overall prevalence of genital herpes infections and could reduce new HIV infections as well, especially in high - burden regions of sub-Saharan Africa.»

The responses of those given the quadrivalent vaccine were the same as those of volunteers who received the vaccine with two strains of A and the strain of B that matched the B strain in the 2012 - 2013 seasonal flu trivalent vaccine.

It is designed to learn more about the immune responses to the vaccine in different populations.