This group's achievement reverses the conventional wisdom that memory B cells are induced by high - affinity cells, possibly greatly influencing
vaccine strategies targeting memory B cells.
Not exact matches
But researchers have had only a blurry picture of gp120's structure — not enough to design well -
targeted drugs or mount an effective
vaccine strategy.
The findings underscore the need for
targeted research to further evaluate manufacturing
strategies and
vaccine antigens and platforms, according to the authors.
Bach2, an important gene for inducing memory B cells, may become an important
target in
vaccine strategies.
The
vaccine was
targeted especially toward the virus strain circulating in Thailand, and it may not show the same effectiveness where the virus is different, such as Africa or the U.S. And even the 31.2 percent fewer cases that it resulted in is hardly an ideal preventative
strategy.
This is no easy task, and a study out in the journal Scientific Reports suggests that one of the most promising
strategies — creating a
vaccine that
targets the «stalk» of a protein that covers the flu virus — is a strong one, but isn't completely bulletproof.
Identifying those two molecular
targets could help in the design of better
vaccine strategies and tumor immunotherapies.»
As a part of VIOLIN, we have developed Vaxign, the first web - based publically available
vaccine target design tool based on bioinformatics analysis of genome sequences using the
strategy of reverse vaccinology.
A key program of VIOLIN is Vaxign, the first web - based publically available
vaccine target design tool based on bioinformatics analysis of genome sequences using the
strategy of reverse vaccinology.
These could include
targeted probiotic therapy, novel
vaccines or
vaccine strategies and new therapeutics to treat LRTI.
Studies conducted and supported by NIAID have led to important new discoveries about the microbes that cause NTDs, the identification of
targets for potential new drugs and
vaccines, and the development of
strategies for controlling organisms that transmit NTD - causing agents to humans.