«Our work so far suggests that this new
vaccine strategy induces a level of virus neutralization about 25 times greater, after a single dose, than one sees in standard vaccines,» Weissman said.
Not exact matches
This group's achievement reverses the conventional wisdom that memory B cells are
induced by high - affinity cells, possibly greatly influencing
vaccine strategies targeting memory B cells.
Bach2, an important gene for
inducing memory B cells, may become an important target in
vaccine strategies.
cruzi T cell immunity, and booster immunization would be an effective
strategy to maintain or enhance the
vaccine -
induced protective immunity against T. cruzi infection and Chagas disease.»
Although an autologous tier 2 NAb response is not sufficient for
vaccine protection against HIV - 1, it may be a necessary step in various
strategies intended to
induce bNAbs.
Beyond the issue of alleviating real and potential shortages of influenza -
vaccine supplies is the possibility of pursuing vaccination
strategies that would
induce optimal immunity among populations of persons who not only are at greatest risk for complications but who also generally do not mount an optimal immune response.
Dr. Schief's work focuses on computation - guided and structure - based design of immunogens and immunization regimens, with the goal of
inducing broadly neutralizing antibodies against HIV and other pathogens that have frustrated traditional
vaccine design
strategies.
In addition, Dr. Webb has been studying new
vaccine strategies to
induce T cell - mediated immune responses.