Sentences with phrase «vaccine study at»

2017 — Began a new multi-site Phase 2 Ebola vaccine study at MHRP sites in Africa evaluating a prime - boost regimen in both healthy and HIV - infected volunteers (Ad26.ZEBOV from J&J; MVA - BN - Filo from Bavarian Nordic)

Not exact matches

In 2015, researchers at the University of Washington's Cancer Vaccine Institute published a study on designing vaccines to prevent breast cancer.
A recent comparative study of worldwide military and social spending indicated how at present 1.3 million dollars per minute on average are spent for military purposes; during the same minute 30 children die for lack of food or simple vaccines (WMSE).
Not only would the new method, tested only in mice, be more convenient but also more effective than the flu shot or nasal spray, according to a study at the International Vaccine Institute in Seoul.
Professor David Salisbury, director of immunisation at the DoH, said: «It's natural for parents to worry about the health and well - being of their children and I hope that this study will reassure them that there is no evidence linking the MMR vaccine to autism.»
In the new study, researchers at the NIAID used a virus - like particle vaccine cocktail that expressed a handful of different subtypes of a key surface protein of the influenza virus: hemagglutinin H1, H3, H5 and H7.
A new study shows pregnant women who get flu shots regularly have a weaker peak antibody response to the vaccine than women who don't get them regularly, though mothers and their babies in both groups were well - protected at the time of delivery.
Dr Alice Forster, study author and Cancer Research UK scientist at University College London, said: «Although around 87 per cent of girls in the UK do have the vaccine it's concerning to see that some girls from some ethnic minority groups feel they don't need to have it.
At Kaiser Permanente Northern California, which conducted the study, the first use of the new DTaP was in the vaccine's fifth booster shot in 1991, followed by its use for the fourth booster the next year.
Moreover, getting a better picture of what the virus looks like and understanding its properties through animal testing and studying patients» blood might help vaccine developers pinpoint specific issues, says Pei - Yong Shi, a virologist at The University of Texas Medical Branch at Galveston.
Sun's study found that children given the vaccine had a six-fold increased risk of a febrile seizure on the day of their first vaccination (given at three months) and a four-fold increased risk on the day of their second vaccination (given at five months).
For thimerosal, the IOM looked at five studies, examining populations in Sweden, Denmark, the United Kingdom, and the United States (studies that vaccine critics contend were flawed).
In the study, a tipping point represented the point at which vaccine coverage declines dramatically due to spreading fear, which could cause large disease outbreaks due to a loss of population immunity.
Although previous studies of similar nanoparticles have found an effect of nanoparticle shape and size on antibody responses, such a trend was not seen at significant levels for the DENV2 - E vaccine.
«Based on epidemiological studies, the 9vHPV vaccine could prevent approximately 90 percent of cervical cancer, 90 percent of HPV - related vulvar and vaginal cancer, 70 to 85 percent of high - grade cervical disease in females, and approximately 90 percent of HPV - related anal cancer and genital warts in males and females worldwide,» explained Anna R. Giuliano, Ph.D., Director of the Center for Infection Research in Cancer at Moffitt.
«We think we can use our molecular, rational design approaches to make a better flu vaccine for people who really need it,» says study leader Andrew Pekosz, PhD, an associate professor in the Department of Molecular Microbiology and Immunology at the Bloomberg School of Public Health.
The researchers, including those from Moffitt Cancer Center, published the final results of a study showing the newest vaccine is highly effective at preventing HPV infection and disease.
The study, which will not be completed for at least five years, will evaluate whether the vaccine prevents tumor recurrence rather than causing shrinkage.
The study involved 10 275 healthy children aged 2 to 14 years who were randomly assigned to receive three injections of the CYD - TDV vaccine (6851) or a placebo (3424) at 0, 6, and 12 months, and followed for up to 2 years.
«It's a novel strategy, and it works beautifully,» said senior investigator Harvey M. Friedman, MD, a professor of Infectious Diseases at Penn. «I know of no other HSV2 vaccine candidate with published results that are as promising as this study
Vaccines are successful in preventing pandemic flu and reducing the number of patients hospitalised as a result of the illness, a study led by academics at The University of Nottingham has found.
«What this study tells us is that if more and more people choose not to get a vaccine,» says Paul Offit, director of the Vaccine Education Center at The Children's Hospital of Philadelphia, «then you'll have bigger and bigger outbreaks.vaccine,» says Paul Offit, director of the Vaccine Education Center at The Children's Hospital of Philadelphia, «then you'll have bigger and bigger outbreaks.Vaccine Education Center at The Children's Hospital of Philadelphia, «then you'll have bigger and bigger outbreaks.»
During the 2012 - 2013 season, when H3N2 viruses were dominant, the high - dose flu vaccine was 36 percent more effective at preventing deaths in the Medicare beneficiaries studied, compared to the standard - dose vaccine.
«This study demonstrates that despite high rates of Tdap vaccination, the growing number of adolescents who have received only the newer acellular pertussis vaccines continue to be at higher risk of contracting whooping cough and sustaining epidemics,» said lead author Nicola Klein, MD, PhD, co-director of the Kaiser Permanente Vaccine Study Cestudy demonstrates that despite high rates of Tdap vaccination, the growing number of adolescents who have received only the newer acellular pertussis vaccines continue to be at higher risk of contracting whooping cough and sustaining epidemics,» said lead author Nicola Klein, MD, PhD, co-director of the Kaiser Permanente Vaccine Study CeStudy Center.
Many individual studies have looked at how effective the available vaccines were at preventing illness and hospitalisation caused by the pandemic influenza strain but up until now no - one has summarised all the available data.
For example, a study just out in The Lancet, funded by the U.S. Food and Drug Administration and focused on Medicare patients, found that the high - dose vaccine was 22 percent more effective at preventing flu - related hospital admissions.
«This vaccine appears to be safe for patients, and elicits a broad anti-tumor immunity — we think it warrants further testing in larger clinical trials,» said study lead author Janos L. Tanyi, MD, an assistant professor of obstetrics and gynecology at Penn Medicine.
Studies have shown that flu vaccines work better at protecting against influenza B or influenza A H1N1 viruses than influenza A H3N2.
The results from the study could be used to help public health officials to plan a more effective response to future pandemics, such as rolling out vaccines at a much earlier time and targeting specific types of vaccines at different age groups.
Professor Ajit Lalvani from the National Heart and Lung Institute at Imperial College London, who led the study, said: «New strains of flu are continuously emerging, some of which are deadly, and so the Holy Grail is to create a universal vaccine that would be effective against all strains of flu.»
Last year the National Institutes of Health announced plans to put some 180 ex-Coulston chimps currently housed at the Alamogordo Primate Facility back in service, to rejoin the roughly 800 other chimps that serve as subjects for studies of human diseases, therapies and vaccines in the U.S., which is the only country apart from Gabon to maintain chimps for this purpose.
During the following season (2013 - 2014), when H1N1 viruses dominated and the standard - dose vaccine had better effectiveness than the previous season, the high - dose vaccine was not significantly better at preventing deaths among the Medicare patients studied.
These findings, which appear in an early online edition of Vaccine, confirmed the expected results, said Geoffrey Gorse, M.D., professor of internal medicine in the division of infectious diseases at Saint Louis University and the study's lead author.
«We are pleased to have demonstrated such a potent and durable immune response to the vaccine,» said the study's lead author, Sita Awasthi, PhD, a research associate professor of Infectious Diseases at Penn. «If found effective in clinical trials, the vaccine will have a huge impact on reducing the overall prevalence of genital herpes infections and could reduce new HIV infections as well, especially in high - burden regions of sub-Saharan Africa.»
But influenza vaccine research completed before that time by Yoshihiro Kawaoka's group at the University of Wisconsin, Madison, may demonstrate «the risk of curtailing so - called [GOF] studies,» wrote Jon Cohen in a Wednesday ScienceInsider.
In 2011, Science's editors will be watching a smaller detector at the Large Hadron Collider called LHCb, which will study B mesons in great detail; new techniques that should lead to the discovery of many more genes contributing to adaptation; an ignited fusion burn at the National Ignition Facility; broadly neutralizing antibodies, which are capable of disabling a wide range of viral variants; the first plug - in hybrid electric cars whose batteries are charged from a wall socket go on the market; and the results of the first phase III trial of a malaria vaccine.
«Delivery of the HPV vaccine in safety - net settings is critically important because uninsured African - American and Hispanic women have higher rates of cervical cancer,» said Dr. Jasmin Tiro, Associate Professor of Clinical Sciences at UT Southwestern, who led the study.
«The ability to identify the glycan fingerprint on HIV's glycoprotein will help us develop a vaccine that matches what is found on the virus,» said James Paulson, Cecil H. and Ida M. Green Chair of Chemistry at TSRI and co-chair of the Department of Molecular Medicine, who led the study published in the journal Nature Communications.
«There is a need to understand what's happening with the existing live vaccine and potentially a need to develop a new one,» said David Topham, Ph.D., Marie Curran Wilson and Joseph Chamberlain Wilson Professor of Microbiology and Immunology at URMC and author of the study.
The new research is at odds with other studies that cleared the vaccine of responsibility.
At the time of this study (2010 - 2011), the vaccine was only recommended for girls.
A few months later, he was working at the International Center for Genetic Engineering and Biotechnology (ICEGB) in Delhi, studying malaria vaccines.
«Now that we know the mice can be vulnerable to Zika infection, we can use the animals to test vaccines and therapeutics — and some of those studies are already underway — as well as to understand the pathogenesis of the virus,» said senior author Michael Diamond, MD, PhD, a professor of medicine at Washington University.
One goal of the study is to demonstrate the prevalence of H. influenzae in the region, explains Joel Ward, director of the Center for Vaccine Research at the University of California, Los Angeles, and scientific adviser to IVI.
«HPV vaccines could dramatically reduce the incidence of HPV - associated cancers, but uptake of these vaccines is far lower than for other routine childhood and teen immunizations,» said Kevin A. Henry, PhD, an assistant professor in the Department of Geography and Urban Studies at Temple University in Philadelphia and member of Fox Chase Cancer Center's Cancer Prevention and Control program.
«An RSV vaccine with this M2 - 2 deletion could tip the balance toward a better immune response, which is what we predicted based on earlier laboratory studies,» says study leader Ruth A. Karron, MD, director of the Center for Immunization Research and a professor in the Department of International Health at the Bloomberg School.
The study included 124 newly diagnosed patients at 25 clinical trial sites in the U.S. Two - thirds of the patients were treated with ICT - 107, an experimental vaccine based on immune system cells called dendritic cells that were exposed to six synthetic proteins, or antigens, known to be involved in GBM development.
Heidi Larson is an anthropologist at the London School of Hygiene and Tropical Medicine who studies public trust in vaccines
In a March 2009 study published in Genes and Immunity, researchers at the National Center for Computational Toxicology compared the genetic signatures of 16 people who experienced smallpox vaccine side effects, including fever, rashes and enlarged lymph nodes, to 45 people who did not.
Researchers at the Kaiser Permanente Vaccine Study Center in Oakland, Calif., studied the medical records of mothers who gave birth to babies between 2010 and 2015.
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