Sentences with phrase «vaccine target design»
A key program of VIOLIN is Vaxign, the first web - based publically available vaccine target design tool based on bioinformatics analysis of genome sequences using the strategy of reverse vaccinology.
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As a part of VIOLIN, we have developed Vaxign, the first web - based publically available vaccine target design tool based on bioinformatics analysis of genome sequences using the strategy of reverse vaccinology.
Not exact matches
But researchers have had only a blurry picture of gp120's structure — not enough to design well - targeted drugs or mount an effective vaccine strategy.
CTL119 manufacturing begins with a patient's own T cells, some of which are removed and then reprogrammed in Penn's Clinical Cell and Vaccine Production Facility with a gene transfer technique designed to teach the T cells to target and kill tumor cells.
The finding could ultimately help improve flu vaccine design: Because it takes time to manufacture vaccines and inoculate the public, scientists must choose which strains to target many months before the year's flu season begins.
Therefore, this could provide an important target for disease interventions or vaccine designs.
Identifying those two molecular targets could help in the design of better vaccine strategies and tumor immunotherapies.»
The ability to design new protein nanostructures could have useful implications in targeted delivery of drugs, in vaccine development and in plasmonics — manipulating electromagnetic signals to guide light diffraction for information technologies, energy production or other uses.
«This helps us understand that process, and it opens up the window to targeting these cells by designing vaccines that prevent autoimmunity.»
This is a very exciting discovery as it offers numerous possibilities of designing therapies and vaccines to target these exposed surfaces to treat dengue as well as other related viruses such as Zika and chikungunya.
«This will allow us to design better inhibitors or vaccines that block invasion by targeting multiple steps at the same time.»
These results may provide new ways for vaccine researchers to target HIV and may influence the design of future HIV vaccines.
More importantly, Gack found that avian, swine, and human flu viruses block TRIM25 to evade immune defense by RIG - I, unraveling a molecular target for the design of antiviral drugs and vaccines.
The findings should help scientists to better understand the immune system, including autoimmune diseases, as well as provide potential new targets for immunotherapy and vaccine design.
My studies of cancer genomes have led to characterization of multiple pediatric and adult tumor types, to development of methods that identify and characterize changes in genomic heterogeneity, to defining acquired resistance mechanisms to targeted therapies and to designing novel, personalized vaccines for individual patients.
«This loss - of - HLA mechanism suggests that, when designing vaccines and cell - based therapies, we need to target antigens that are presented to the immune system,» says Swanton.
«Seeing the design of this key protein provides a target for a potential vaccine or even a therapeutic drug,» Smith said.
Physicians with the Personalized Medicine Program at The Tisch Cancer Institute have initiated a phase I proof - of - concept study, a fully personalized multipeptide therapeutic vaccine designed to target tumor - derived neoantigens for individual patients.
Animal Friends» Clinic Services Program consists of three core components each uniquely designed to support a targeted population by offering pets high - quality, low - cost spay / neuter, vaccines and wellness services.
VANGUARD ® crLyme is a multivalent vaccine which contains an OspA protein and a single OspC protein that is composed of antigenic material from seven common types of OspC found in Lyme - infected dogs in the U.S. 1 Its uniquely targeted design helps provide a broad spectrum of coverage while delivering a low - reactive vaccine by minimizing the amount of extraneous proteins administered to the dog.
About Vanguard crLyme Vanguard crLyme is a next - generation multivalent vaccine which contains outer surface protein A (OspA) protein and a single OspC protein that is composed of antigenic material from seven common types of OspC found in Lyme - infected dogs in the U.S. 1 Its uniquely targeted design helps provide a broad spectrum of coverage while delivering a low - reactive vaccine by minimizing the amount of extraneous proteins administered to the dog.