Not exact matches
The
vaccine was most effective against H3N2, increasing antibody
titers (a measure how much antibody is produced
after vaccination) fourfold in more than 81 percent of who received it, according to the company.
All
vaccine groups exhibited lower
titers or no detectable virus on day two
after challenge.
Two days
after challenge with 106 TCID50 of SARS - CoV,
titers in mice given PBS varied between 107.0 and 108.0 TCID50 per g of tissue; one vaccinated animal in the group given the S protein
vaccine (SV) at the 3 µg and the 1 µg dosage without alum yielded virus but all other animals in all other groups were culture negative for virus (figure 3B).
All groups given the S protein
vaccine (SV) yielded virus
after challenge and the differences between groups were significant (p = 0.002 for all groups, p = 0.023 for alum and p = 0.008 for no adjuvant, Kruskall - Wallis); also, geometric mean
titers were higher for the groups given lower
vaccine dosages.
In multiple regression analysis,
titers were also significantly increased
after both the DI and S protein
vaccines with use of alum (p ≤ 0.01); no dosage effect was noted.
B. Geometric mean virus
titer (log10 TCID50 / g) and standard error of the mean (S.E.) in lungs on day 58 (two days
after SARS - CoV challenge for each
vaccine dosage group for each mouse strain.
While increased
titers of serum antibody were induced and no virus was detected day two
after challenge in most animals, the Th2 - type immunopathology occurred
after challenge, and the immunopathology seen earlier
after vaccination with the DI whole virus
vaccine was seen again.
If a high
titer vaccine is used, there is still virus left over
after all the maternal antibody has been used up.
When a high
titer vaccine is used, there is still virus left over
after all the maternal antibody has been used up.
After one of our dogs had a
vaccine reaction and the other, whose immunity testing indicated she was prone to vaccinosis, we loaded up on
titering education.
On completion of the puppy core vaccination series with the last dose given at 14 - 16 wk of age, a dog can be expected to have an antibody
titer or positive test result, regardless of the serologic test performed, provided the serum sample is collected > 2 wks
after the last dose of
vaccine.»
Question: Some vets do not recommend booster
vaccines and rabies
after a certain age, maintaining (sometimes via
titer testing) that the dog's immunity is satisfactory.
After a puppy has completed the initial
vaccine series and annual boosters, we routinely
titer these patients for distemper and parvovirus.
And, if vets shouldn't be allowed to charge a fee for something that has been proven to be ineffective, then you should ask for your money back if your dog has been vaccinated for the core
vaccines (parvo, distemper and adenovirus)
after 16 weeks of age or without a negative
titer test.
Immunity can not be assumed during the puppy vaccination series until approximately 2 weeks
after using a high
titer vaccine at 12 weeks of age or a lower
titer vaccine at 16 weeks of age PLUS a 5 day to 14 day period to allow the immune system to respond.
Since it takes 7 - 10 days for the immunity to form, if you test
titers ten days
after a parvo and / or distemper
vaccine, you will know if the puppy had an immunizing response.
I have been having
titers drawn for years on my dogs
after one of them had a reaction to the Lepto
vaccine two years in a row.
Consider vaccination antibody
titers for adult and senior dogs and cats, and for sensitive pets that have previously had a reaction such as fever or swelling
after receiving a
vaccine.
After 3 - 4 years of age, we recommend
vaccine titers for all
vaccines except for rabies.