Sentences with phrase «vaccine trial»

He suggests one option may be to recruit «sleeper sites» for vaccine trials across the globe.

Throughout the years, there have been a multitude of vaccine trials, nearly all with mixed results.

Most other vaccine trials have tried to use the malaria parasite — rather than the body's reaction against it — to find possible targets for vaccines.

Indeed, recent vaccine trials have shown evidence of severe disease in some recipients who were previously exposed to virus.

The NIH formed its own HIV vaccine trial network in 2000 to oversee clinical research sites in the U.S., Africa, Asia, the Caribbean and South America.

Dr. Nishila Moodley, left, receives an achievement award from her mentor, Dr. Glenda Gray, before 700 members of the HIV Vaccine Trials Network in Washington, D.C.

«This finding is consistent with a hypothesis generated out of the follow - up studies to the RV144 HIV vaccine trial in Thailand that showed the first efficacy in humans,» noted COL Nelson Michael, Director of the U.S. Military HIV Research Program at the Walter Reed Army Institute of Research.

«The RV247 study represents the first Ebola vaccine trial conducted in Africa.

Emmanuel Lansana, 43, takes part in a briefing before becoming the first person to be injected in the Ebola vaccine trials launched in Monrovia, Liberia, in February 2015.

It was the largest AIDS vaccine trial ever, with thousands of participants.

Audran R, Cachat M, Lurati F, Soe S, Leroy O, Corradin G, Druilhe P, Spertini F. Phase I malaria vaccine trial with a long synthetic peptide derived from the merozoite surface protein 3 antigen.

CRI: How did you learn about the cancer vaccine trial at Roswell Park?

Working together — governments, academic institutions, non-profits, private industry, scientists, clinicians, advocates, and HIV vaccine trial participants — it is conceivable we will realize an effective vaccine in the next decade.

July 2016: Two human vaccine trials begin, one led by the U.S. National Institutes of Health and a second by U.S. company Inovio Pharmaceuticals and South Korean firm GeneOne.

The start of the three - year vaccine trial involving 2,600 women in southern Africa means that for the first time in more than a decade there are now two big HIV vaccine clinical trials taking place at the same time.

In WRAIR's first vaccine trial, all the participants were «my friends in the laboratory or from down the hall,» says Ballou, and they went home after being infected.

10/7/2008 Novel Lung Cancer Vaccine Trial Launched at Moores UCSD Cancer Center Oncologists at the Moores Cancer Center at the University of California, San Diego (UCSD) in La Jolla are hoping to stave off the relentless march of advanced lung cancer by treating patients with a novel kind of cancer vaccine.

In 2009, the RV144 Thai vaccine trial provided the first evidence in humans that a safe and effective preventive HIV vaccine is possible.

Led by Nina Bhardwaj, M.D., director of immunotherapy, the Personalized Genomic Vaccine trial uses the genetic sequence of a patient's tumor to create a customized vaccine.

At Taksin Hospital he fine - tunes the experiment - a «placebo - controlled double - blind trial» - so far the only full - scale Aids vaccine trial ever.

The Final (Oral Ebola) Vaccine Trial on Captive Chimpanzees?

There are some specific GBS insights scientists can use for future vaccine trials.

The results came as a surprise to HIV - vaccine skeptics in the AIDS (acquired immunodeficiency syndrome) research field, whose numbers have increased after years of failed vaccine trials.

In their new study, researchers from the Johns Hopkins Bloomberg School of Public Health, Imperial College London and the University of Florida re-analyzed data from vaccine trials conducted in 10 countries with more than 30,000 participants as well as recently published data on the long - term follow - up of these participants.

The Army - led RV144 HIV vaccine trial provided the first evidence in humans that a safe and effective preventive HIV vaccine is possible.

In the HPV vaccine trial which was suspended after 6 deaths last year, the government inquiry concluded that consent forms had actually been signed by wardens of hostels where the girls resided and not by the girls themselves.

Chris Plowe at the University of Maryland in Baltimore, who works on AMA - 1 vaccines, says agencies that fund vaccine trials do not test for effects on pathogens beyond monitoring for immune escape.

That has been a persistent problem for those trying to target β amyloid using immunotherapies — a β amyloid vaccine trial many years ago was halted because it triggered dangerous brain inflammation.

Kapikian and his colleagues decided to set up their own vaccine trial in a poor urban area near Caracas, Venezuela, with a 10-fold stronger dose of the vaccine.

See an interview with an RV247 Ebola vaccine trial volunteer.

«TB vaccine trial is step forward though results «not what hoped,»» said Oxford University's news team.

When results from a landmark tuberculosis vaccine trial in Cape Town, South Africa were published in The Lancet in February 2013, the headlines were grim, despite hopes that the trial would point toward a successful way to thwart one of the globe's biggest public health threats.

Even concerns about GBS, a condition treatable with pricey therapies including plasma exchange or injections of immunoglobulins, can not push back vaccine trials.

Other promising vaccine trials include those for WT1 for leukemia (GSK) and Onyvax - P for prostate cancer (Onyvax in London), on top of ongoing studies of Provenge.

The results of the early - stage vaccine trial suggest that the preventive treatment should be developed further and that scientists are a step closer to being able to counter a potential H7N9 flu pandemic using a clinically tested vaccine, researchers argue April 30 in Science...

«Many adenovirus vaccine trials are moving forward for HIV, malaria and TB with promising results and very few residual safety concerns,» he said.

Science's picks for Areas to watch in 2017 are human embryo research, Zika vaccine trials, the search for Planet Nine, and the impacts on research of the U.S. election and «Brexit» vote.

«Past HIV vaccine trials reveal new path to success.»

Tomaras and colleagues examined two HIV vaccine trials previously conducted in Thailand.

Young researchers can move from lab work to supervising vaccine trials, while postdocs can find themselves coordinating in - house research with work outsourced to academic labs, says Hanneke Schuitemaker of Crucell.

Of more than 50 therapeutic vaccine trials so far, this is the first one that has bolstered the immune system in a «meaningful» way, says Steven Deeks, an HIV / AIDS clinician and researcher at the University of California, San Francisco, who is «cautiously optimistic» that the data will inspire others to study the approach.

To do this, vaccine trials now use microarrays of DNA sequences to track which genes get turned on or off in response to a vaccine.

Vaccine trials started last week, and initial observations are promising, but Donnelly and her team warn that it will take many months to scale up production sufficiently to start having an effect on the current epidemic.

«The immune response and the safety so far have put these out there further than the other candidates we have,» says infectious disease specialist Scott Hammer of Columbia University, part of the team designing the VRC vaccine trial.

Cholera expert David Sack of Johns Hopkins University in Baltimore, Maryland, doubts that immunity wanes as quickly as the data suggest — vaccine trials indicate it may last several years.

In the mouse experiments, researchers conducted five independent vaccine trials in which mice were vaccinated with the novel antigen, which they have designated as Schizont Egress Antigen - 1 (PfSEA - 1) or control.

«Future neoantigen vaccine trials will recruit more patients with advanced disease to test the efficacy of the vaccine, take advantage of improved methods for predicting antigen presentation to boost the number of effective neoantigens and test for synergy with checkpoint blockade and other immunotherapeutics,» the scientists said.

Researchers have begun building model immune systems using human cells, and this lab technique should make early vaccine trials quicker, safer and cheaper, according to scientists in the United States and Britain involved in this novel approach.