Sentences with phrase «vaccine trial conducted»

In a parvo vaccine trial conducted by Dr Ronald D Schultz, head of pathobiology at Wisconsin University, three out of six parvo vaccine brands totally failed to give protection; two gave only partial protection; and only one was shown to be effective.

«The RV247 study represents the first Ebola vaccine trial conducted in Africa.

In their new study, researchers from the Johns Hopkins Bloomberg School of Public Health, Imperial College London and the University of Florida re-analyzed data from vaccine trials conducted in 10 countries with more than 30,000 participants as well as recently published data on the long - term follow - up of these participants.

Not exact matches

The company plans in October to conduct a separate test specifically to study the seasonal flu vaccine's effectiveness among 480 elderly participants (a demographic often encouraged to get seasonal flu shots), and Phase III efficacy trials across a larger set of demographics are scheduled to begin early next year.

Armed with the knowledge of how to study vaccines appropriately, scientists ideally should have no trouble conducting proper trials.

And scientists who conduct human challenge studies, which typically involve a few dozen participants, say they have critical benefits: In addition to saving time and money, they can reveal harm caused by a potential drug or vaccine before it enters large - scale human efficacy trials.

A new type of cancer vaccine has yielded promising results in an initial clinical trial conducted at the Perelman School of Medicine at the University of Pennsylvania and the Abramson Cancer Center of the University of Pennsylvania.

Sadoff says clinical tests of spray - dried BCG could begin as soon as late 2008, when his group plans to conduct mid-stage trials of several new forms of the vaccine.

Healthy adults mounted strong immune responses after receiving an investigational whole inactivated Zika virus vaccine, according to interim analyses of three Phase 1, placebo - controlled, double - blind trials conducted at Beth Israel Deaconess Medical Center (BIDMC), Walter Reed Army Institute of Research (WRAIR), and Saint Louis University School of Medicine.

In 1967 and 1968, Yugoslavia conducted a mass polio vaccination campaign using polio virus propagated in WI - 38 cells; Sweden and Switzerland had already run trials of the same vaccine.

An experimental vaccine to prevent the mosquito - borne viral illness chikungunya elicited neutralizing antibodies in all 25 adult volunteers who participated in a recent early - stage clinical trial conducted by researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

China is to be the first non-Western country to conduct a trial of an experimental AIDS vaccine.

Phages would require a less traditional approach to get official approval, such as the annual process for influenza vaccines in which manufacturers secure approval of new formulas based on the flu bug that is going around that year, instead of conducting big clinical trials every time.

The Johns Hopkins scientists who conducted the trial said the finding is significant because measuring immune system responses directly in the lesions may be a more accurate way to evaluate so - called «therapeutic» vaccines than by the conventional means of blood analysis.

Huttner and colleagues conducted a Phase 1 trial of the vaccine in 2014 - 2015 in Switzerland.

For this study, the Swiss researchers pooled data with two other groups that conducted Phase 1 trials of the vaccine in Africa — in Lambaréné, Gabon, and Kilifi, Kenya.

The group partnered with governments and vaccine makers to conduct trials outside of the U.S., which now account for nearly half of the 30 - plus trials currently underway.

While conducting trials, researches also found that some manufacturers» formulations for their one - year and three - year rabies vaccines were identical.

The second phase of clinical trials of the vaccine are underway in Brazil, conducted by Orygen Biotecnologia SA, and the Infectious Disease Research Institute, Seattle.

To date, the Network has conducted the majority of the published, presented, or ongoing clinical trials of preventive HIV vaccines worldwide.

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), helped identify the viral strain used in the ZPIV vaccine, supported the preclinical safety testing, and is sponsoring the conduct of this trial.

Being both tumor - specific and widely expressed in human tumors, MAGE - A3 is an ideal cancer vaccine target and will be the focus of many clinical trials, including the largest clinical trial ever conducted in lung cancer, MAGRIT, launched by GlaxoSmithKline in 2007.

In 1999, Wolchok received a grant from CRI to conduct a clinical trial of a xenogenic vaccine in humans with melanoma.

The HVTN is an international collaboration that conducts all phases of clinical trials, from evaluating experimental vaccines for safety and the ability to stimulate immune responses, to testing vaccine efficacy.

Human challenge trials like this one are an extremely efficient way for scientists to tell whether a particular vaccine is effective, but they are rarely conducted because of the ethical dilemma of the risk it places on volunteers who are purposely exposed to a virus.

Also scheduled for this fall is a large - scale clinical trial of an HIV vaccine, which will be conducted in South Africa and co-funded by NIH.

In the new issue of IAVI Report we wrote about how researchers at the AIDS Vaccine 2010 conference in Atlanta discussed the limited window of opportunity for conducting clinical trials to test partially effective HIV prevention strategies, including HIV vaccine candidates and oral or topical antiretroviral pre-exposure prophylaxis (PrEP), in combiVaccine 2010 conference in Atlanta discussed the limited window of opportunity for conducting clinical trials to test partially effective HIV prevention strategies, including HIV vaccine candidates and oral or topical antiretroviral pre-exposure prophylaxis (PrEP), in combivaccine candidates and oral or topical antiretroviral pre-exposure prophylaxis (PrEP), in combination.

Together these data will support future efforts to conduct Phase I clinical trials in humans and constitute significant progress on the pathway toward a vaccine for falciparum malaria.

The findings have led to the first primary vaccine study that we are conducting as a multi-center international trial.

The trials will be conducted by the publicly funded, Hutch - based HIV Vaccine Trials Network, or HVTN, the largest global network striving to develop vaccines to prevent HIV /trials will be conducted by the publicly funded, Hutch - based HIV Vaccine Trials Network, or HVTN, the largest global network striving to develop vaccines to prevent HIV /Trials Network, or HVTN, the largest global network striving to develop vaccines to prevent HIV / AIDS.

Clinical trials with SARS coronavirus vaccines have been conducted and reported to induce antibody responses and to be «safe» [29], [30].

Since then, Aeras has helped develop 9 TB vaccine candidates and conducted over 35 Phase 1 - 2b clinical trials.

MHRP's international research program has six clinical research sites in the U.S., Africa and Asia, where it conducts HIV cohort studies, HIV vaccine trials and therapeutic studies.

The HIV Vaccine Trial Network (HVTN) plans to conduct clinical trials in heterosexual adults that will evaluate a prime - boost vaccine regimen similar to that used in RV144 adjusted to target the most common subtype of HIV in the region (subtVaccine Trial Network (HVTN) plans to conduct clinical trials in heterosexual adults that will evaluate a prime - boost vaccine regimen similar to that used in RV144 adjusted to target the most common subtype of HIV in the region (subtvaccine regimen similar to that used in RV144 adjusted to target the most common subtype of HIV in the region (subtype C).

To address this growing problem, NIAID is funding and conducting research on many aspects of antimicrobial (drug) resistance, including basic research on how microbes develop resistance, development of new and faster diagnostics, and clinical trials designed to find new vaccines and treatments effective against drug - resistant microbes.

In this role, Ms. Roxland re-launched and chaired J&J's Ethics Committee, created an enterprise - wide consultation service for teams and individuals confronting complex research ethics issues, and provided guidance on issues such as post-trial access for former research participants, conducting clinical trials in war - torn regions, testing of a potential Ebola vaccine during a public health crisis, commercialization of stem cell therapies, subject recruitment and withdrawal, and expanded access / compassionate use.

Its Clinical Trials Center conducts 13 - 15 clinical studies per year, and in December initiated a Phase 2 clinical trial of an Ebola vaccine following its groundbreaking first - in - human testing of the Ebola vaccine that showed efficacy in Guinea last year.

MUWRP was selected by the NIAID to conduct RV 247 based on their expertise in conducting HIV vaccine trials.

He is using lymphocyte receptors as targets for new therapies for lymphoma, and is currently conducting clinical trials of lymphoma vaccines.

Results from the first Ebola vaccine clinical trial conducted in Africa (in 2009 - 2010) reveal a vaccine candidate produces the same immune response seen in the United States in an African setting.

MHRP conducted the first Ebola vaccine clinical trial in Africa.

The trial, conducted in Uganda, also demonstrated that the vaccines for the Ebola and Marburg viruses could be combined safely.

«The biggest hurdle will be conducting safety trials in the most important target population — women who are pregnant or planning pregnancies,» said Dr. Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine and president of the Sabin Vaccine Institute.

Yet the pace of HIV vaccine research is now growing so swiftly that the scientific goal of conducting and completing a clinical trial may be threatened by a higher ethical obligation — to inform those taking part in the study that the original scientific basis for the research may have been modified by later work.

The department has developed and produced 15 different formulations for early clinical trials (e.g. vaccine antigens produced by heterologous expression) and has conducted more than 20 clinical trials as sponsor.

Glenda Gray, executive director of the Wits Health Consortium's perinatal HIV research unit in South Africa, presented data today at the HIV R4P conference in Cape Town indicating that the prime - boost vaccine candidates initially tested in the RV144 trial in Thailand — the only HIV vaccine trial to date to show any efficacy — induced cross-clade immune responses in a Phase I safety trial conducted in South Africa, with immunogenicity similar to or greater than that of the responses induced in Thai volunteers.

USAID's investments have been put to work by IAVI to enable both AIDS vaccine research and the cultivation of scientific and technical capacity at clinical research centers in developing countries that conduct vaccine trials in partnership with the organization.

Avigan and his colleagues have secured funding to perform a larger clinical trial for their leukemia vaccine, and also are conducting a trial for a vaccine against multiple myeloma, another blood cancer.

Numerous clinical trials involving the use of melanoma tumor vaccines have been conducted or are underway.