The mosquito - borne disease caused by the Plasmodium parasite kills more than 700,000 people every year, the vast majority of them African children, and no
vaccine has
ever shown efficacy in
trials.
Being both tumor - specific and widely expressed in human tumors, MAGE - A3 is an ideal cancer
vaccine target and will be the focus of many clinical
trials, including the largest clinical
trial ever conducted in lung cancer, MAGRIT, launched by GlaxoSmithKline in 2007.
«After two years of analyzing the results of the largest AIDS
vaccine clinical
trial ever held — called RV144 — researchers say they have found two ways the immune system can respond, which could predict whether those inoculated will be protected or are more likely to become infected with HIV.»