Sentences with phrase «vaccine trial involving»
The vaccine trial involved scheduled contact visits at 30 — 37 weeks» gestation and at 1, 2 and 7 months postpartum, during which self - reported data on maternal and household smoking behaviours (potential confounding factors) were routinely collected by a trained research assistant and entered into a centralised database.
https://www.mja.com.au/ Not exact matches
That's because a trial like this one is almost without precedent in modern medical research: It involves giving children a vaccine that is almost certain not to benefit them, and that might harm them, all to protect other children from an unlikely scenario — a large - scale anthrax attack.
And scientists who conduct human challenge studies, which typically involve a few dozen participants, say they have critical benefits: In addition to saving time and money, they can reveal harm caused by a potential drug or vaccine before it enters large - scale human efficacy trials.
The study included 124 newly diagnosed patients at 25 clinical trial sites in the U.S. Two - thirds of the patients were treated with ICT - 107, an experimental vaccine based on immune system cells called dendritic cells that were exposed to six synthetic proteins, or antigens, known to be involved in GBM development.
Tested in a U.S. - sponsored trial that involved more than 16,000 volunteers in Thailand, the vaccine was administered in six injected doses starting in 2006 to half of the group, and the other half received a placebo.
Antibody action Only an efficacy trial involving people at risk of infection can reveal whether a vaccine prevents infection.
An earlier form of the vaccine was used in the DarDar Trial, a seven - year study in Tanzania sponsored by the U.S. National Institutes of Health involving patients with HIV infection who at birth had received BCG, the current tuberculosis vaccine.
A major theme is translational research involving the rapid early - stage development and assessment of new vaccines in clinical trials.
Phase III trials involve thousands of participants and occur only after the experimental vaccine has successfully moved from a Phase I and Phase II trial.
Conduct large - scale clinical trials involving high - risk populations to determine the full effectiveness of the vaccine.
Kyle Rybczyk: HIV vaccine trial clinic coordinator will «never regret being involved in this work» September 19, 2017
Immune responses of patients could point way forward for future vaccines.In the latest study, researchers involved with the trial at Mahidol University in Bangkok and the U.S. Military HIV Research Program in Washington DC assembled a team to scour the blood of trial participants for immune indicators that differed between 41 people who received the vaccine and contracted HIV and 205 participants who did not become infected.
Numerous clinical trials involving the use of melanoma tumor vaccines have been conducted or are underway.
A senior spokesperson from a CRO has firsthand experience of almost winning a contract to an Ebola vaccine research trial by one of the big pharmaceutical companies involved.