Sentences with phrase «vaccine virus yield»

However, Kawaoka points out that more testing is required to discern whether they would increase vaccine virus yield under industrial conditions.

Not exact matches

Within several weeks, we had a high - yielding virus [and] I had the vaccine virus made.

Unfortunately, this process is fraught with problems: It's slow (the eggs typically need to incubate for about half a year), inefficient (on average, it takes one to two eggs to yield a single dose of vaccine), and unreliable: Not only can the eggs spoil, but they may also produce the virus at varying rates.

A clinical trial in which volunteers were infected with dengue virus six months after receiving either an experimental dengue vaccine developed by scientists from the National Institutes of Health (NIH) or a placebo injection yielded starkly contrasting results.

Kieny said that for reasons that aren't fully understood, vaccine companies that use eggs to grow vaccine viruses get yields of only 25 % to 50 % of those obtained during the production of seasonal vaccine.

During the 2014 - 15 flu season, the poor match between the virus used to make the world's vaccine stocks and the circulating seasonal virus yielded a vaccine that was less than 20 percent effective.

Two days after challenge with 106 TCID50 of SARS - CoV, titers in mice given PBS varied between 107.0 and 108.0 TCID50 per g of tissue; one vaccinated animal in the group given the S protein vaccine (SV) at the 3 µg and the 1 µg dosage without alum yielded virus but all other animals in all other groups were culture negative for virus (figure 3B).

All groups given the S protein vaccine (SV) yielded virus after challenge and the differences between groups were significant (p = 0.002 for all groups, p = 0.023 for alum and p = 0.008 for no adjuvant, Kruskall - Wallis); also, geometric mean titers were higher for the groups given lower vaccine dosages.

Much of the laboratory's efforts on developing a new preventative vaccine for rabies — a disease that retains a disastrous presence in places across the globe — have yielded useful technologies that the Ertl laboratory is applying to combating other viruses.

None of the animals given any of the alum - adjuvanted DI vaccine (DIV) dosages and only an occasional animal in the lower dosages of nonadjuvanted vaccine yielded virus (Kruskall - Wallis and Mann Whitney U tests, p > 0.05 for all comparisons).

Gack says her goal is to continue to unravel molecular mechanisms that might someday yield antiviral vaccines and drugs not only for emerging and re-emerging viruses but also tumor - inducing viruses, such as certain herpesviruses and human papillomaviruses.

«It may still not be perfect, but it will at least be substantially better than current vaccines,» says Kawaoka, who notes no one else has successfully tried to produce high - yield influenza B vaccine virus before now.

Last year, his research team created a high - yield influenza A vaccine virus candidate for cell culture production.

«As a veterinarian, I am committed to finding a solution, including quick - yielding diagnostic tools and efficacious vaccines, that can control this devastating virus,» said Michael Senn, DVM, MS, Manager, Pork Technical Services, Zoetis.