A modeling - based comparison of broad - spectrum influenza
vaccines against conventional, strain - matched vaccines» by Rahul Subramanian et al. published in PLOS Computational Biology on Thursday 15 December 2016.
They analyzed the genetic data using a statistical method called sieve analysis honed at Fred Hutch for evaluating
vaccines against another genetically variable pathogen, HIV.
Alexandre Marques from Brazil's Universidade Federal de Minas Gerais collaborates with M. G. Finn at Georgia Tech on the development of
vaccines against potentially deadly tropical diseases that are spreading northward due to global warming.
Results from Sanjabi's study could also impact efforts to develop
vaccines against various viruses.
Wistar scientists developed life - saving
vaccines against rabies, rubella, and more recently rotavirus, the most common cause of infantile and childhood diarrhea and death around the world.
The Wistar team is involved in the development of DNA - based
vaccines against EVD and a DNA - based monoclonal antibody (DMAb) to treat EVD.
She completed her doctorate work in Dr. Ian Orme's laboratory where she focused on the development of several novel
vaccines against M. tuberculosis.
Through this, we will accelerate the development of
vaccines against bacterial infections, particularly those relevant to LMICs.
The recent outbreaks of whooping cough in the state have prompted North Carolina health officials to make
the vaccines against the disease available for free to anyone age 7 and older, regardless of whether they have health insurance.
Her research involves preclinical immunology and efficacy of
vaccines against H5N1 pandemic influenza, malaria, and Mycobacterium tuberculosis using mouse, ferret and guinea pig models.
Dr. Baldwin has been at IDRI for over six years and currently works on projects related to development of next - generation
vaccines against infectious diseases.
Scientists could be one step closer to developing long - awaited
vaccines against viruses such as Zika, West Nile or HIV, thanks to research at Penn State College of Medicine.
Dr. Gajewski has developed experimental
vaccines against melanoma that are currently in Phase II clinical trials in a handful of patients at the University of Chicago Hospitals.
Dr. Gajewski has been awarded the grant to pursue his investigation of
vaccines against a type of skin cancer called melanoma.
A study published in Nature reports the results of trials of two potential
vaccines against the Zika virus in mice.
He was chief of Microbiology and Immunology and of Vaccine Research and Development at the World Health Organization and was deeply involved in the coordination of research aiming at the development of
vaccines against diseases of major importance.
Combining Viral Vectored and Protein - in - adjuvant
Vaccines Against the Blood - stage Malaria Antigen AMA1: Report on a Phase 1a Clinical Trial.
Although the IL - 15 plus retinoic acid combination leads to inflammation and tissue damage in those at risk for celiac disease, the authors suggest that for those who are less genetically susceptible, the same combination could help enhance
vaccines against several bacterial infections that cause diarrheal diseases.
This understanding of how HIV - 1's «invisibility cloak» works could lead to the development of effective
vaccines against HIV - 1.
We have focused our bioinformatics research efforts on the study of host - pathogen interactions (HPI) and
vaccines against infectious diseases.
Based on their expertise in immunology and pathology and the available infection models,
vaccines against most relevant viral and bacterial animal infections can be tested.
The scientific work at the HZI Department of Vaccinology and Applied Microbiology includes the elucidation of mechanisms of host responses to infection and vaccination, discovering new mucosal adjuvants, and developing and validating
vaccines against specific infectious diseases.
But Balin says that attempts to create
vaccines against strains of herpes and chlamydia found in the brains of Alzheimer's patients have proven difficult, and there's nothing currently on the horizon.
New
vaccines against malaria, tuberculosis and HIV are currently in field trials in the developing world.
It was founded in November 2005 to develop innovative
vaccines against major global diseases.
EVI's mission is to lead European efforts to develop effective, accessible, and affordable
vaccines against diseases of poverty.
The story of development of
vaccines against rubella and other childhood diseases in the 1960s pits a daring young biologist against his world - famous boss, testing that used prisoners, intellectually disabled children, and other disenfranchised subjects, political roadblocks that nearly derailed the research, and other elements of high drama.
The discovery could help to explain why
vaccines against hepatitis B fail to work in some individuals and may help to identify those people who need extra protection.
Department researchers are developing new
vaccines against these viruses and in identifying small molecular weight compounds for use as antivirals.
This new discovery, funded by multiple groups, opens up novel possibilities for future research aimed at developing
vaccines against these viruses to prevent type 1 diabetes.
Some of them have also been linked to human type 1 diabetes raising the possibility of developing
vaccines against these viruses to prevent some of the new cases of type 1 diabetes.
This combined with the success of antibody - inducing
vaccines against other pathogens suggested that a vaccine that can induce neutralizing antibodies at sufficient titers could protect against HIV [15].
The largest corporate - funded medical trials in history indicate that two new
vaccines against rotavirus, a leading cause of childhood mortality worldwide, are both effective and safe.
While the biodefense enterprise is awash in cash, experts have repeatedly told the government that BARDA's $ 100 million annual budget is too tiny for its ambitious mission: developing and acquiring
vaccines against a host of deadly infectious diseases.
GSK, which has invested more than $ 300 million in RTS, S to date, has pledged to keep the price as low as possible — just manufacturing costs plus a small return to be reinvested in development of second - generation malaria vaccines or
vaccines against other neglected tropical diseases.
He then became a principal investigator at the National Cancer Institute where he studied novel methods for developing
vaccines against tumors and viruses.
Together the results support further evaluation of pre-F
vaccines against RSV in both cattle and in humans, the authors write.
New
vaccines against pneumococcus (pneumococcal conjugate vaccines [PCVs]-RRB- and against rotavirus were recently introduced and each showed great impact on the disease it was addressed to reduce.
But NIAID Director Anthony Fauci says «it is very likely» that Kawaoka's group would have been granted an exemption and continued to receive funding because the study specifically aims to improve
vaccines against influenza.
Candidate
vaccines against Ebola or malaria — one of which recently received an important stamp of approval in Europe — should definitely be used if they are safe and effective, he says, but they could lead to more virulent pathogens.
«New candidate
vaccines against the plague.»
A group at the University of Oxford led by pediatrician Andrew Pollard has conducted a challenge study of experimental
vaccines against typhoid and paratyphoid.
«Consistent with other
vaccines against meningococcal disease, a waning of hSBA titres was observed after infant vaccination with 4CMenB.
Molecular biologists at Philadelphia's INB: Biotechnologies are using the vegetable to make
vaccines against anthrax, influenza, even plague.
The company is now developing
vaccines against ragweed, house dust mites, Japanese cedar and pollen.
Effective preventive
vaccines against the most oncogenic forms of HPV have been available for a number of years, with vaccination having the long - term potential to reduce the number of cases of cervical cancer,» said NCI Acting Director Douglas Lowy, M.D.
Instead of working through antibody - mediated immunity, Liang says successful prophylactic
vaccines against the virus might have to work through cell - mediated immunity, which means immune cells are taught to attack infected cells.
Despite the widespread use of screening programs and the recent advent of
vaccines against human papilloma virus, cervical cancer continues to be a significant public health problem.
Kang's primary research focuses on designing and developing effective
vaccines against viral diseases such as influenza virus and RSV, but he partnered with a university and research institutes in South Korea that wanted international collaborative projects to study if ginseng can be used to improve health and protect against disease because of the potential benefit in fighting these viruses.
Despite this, some parents are refusing to allow their children to be vaccinated out of fear that certain vaccines cause autism, or that combined
vaccines against several diseases overload the immune system.