«That's further evidence that BamE may be a new
vaccine target against N. gonorrhoeae,» Sikora said.
Not exact matches
H. contortus has become resistant to all major treatments
against parasitic worms, so its genome is a good model to understand how drug resistance develops in this complex group of closely related parasites and will also reveal further potential drug and
vaccine targets.
Previous infection with one serotype of dengue, or protection
against just one serotype, can lead to more severe disease if a person contracts other serotypes, so it's vital that
vaccines are available that specifically
target all four strains.
It is also a whole - tumor
vaccine, meant to stimulate an immune response
against not just one tumor - associated
target but hundreds or thousands.
«The microgravity environment of the International Space Station is now being used for myriad lines of research, for example:
vaccine development, finding novel molecular
targets against drug - resistant pathogens, and testing of molecules to be used
against osteoporosis or cancer,» Zea says.
Because the
vaccine causes the body to mount an immune response directed
against a unique tumor, the therapy is much more effective than gene -
targeted or more general chemotherapy alone.
A
vaccine against meningitis has an unexpected side effect: It appears to
target gonorrhea, too.
2005 - 2006 — Merck and GSK report that the two HPV
vaccines made from viruslike particles are 100 percent effective
against the
targeted HPV strains.
Another possibility that Irvine's lab is working on is developing treatments that could be used
against tumors even when scientists don't know of a specific
vaccine target for that type of tumor.
Childhood
vaccines are recommended worldwide, based on their protective effect
against the
targeted diseases.
Once in the lymph nodes, these
vaccines can stimulate production of huge numbers of T cells
against the
vaccine target.
The work should help provide
targets for better drugs
against S. pneumoniae, which is increasingly becoming resistant to existing therapies, as well as
vaccines.
One factor is cross protection, which is the
vaccine's ability to protect
against additional HPV types that it does not directly
target.
Most other
vaccine trials have tried to use the malaria parasite — rather than the body's reaction
against it — to find possible
targets for
vaccines.
The structure could inform
vaccine development, as the Zika E glycoprotein is a key
target of immune responses
against the virus.
We assess spontaneous and
vaccine - induced immune responses
against melanoma, and have a particular interest in developing methods for understanding functional subpopulations within melanoma and the optimal ways of
targeting them therapeutically.
'» In all patients who were vaccinated, his team found tumor -
targeting T cells, and he noted that in addition to augmenting pre-existing T cell responses, the
vaccine also stimulated new T cell responses
against tumors.
At first, analyzing a patient's surgically removed tumor and developing a
vaccine against 10 specific
targets on the tumor took nine months, says Greg Lizée, Ph.D., associate professor of Melanoma Medical Oncology, whose research focuses on the immune system.
Influenza
vaccines that better
target the influenza surface protein called neuraminidase (NA) could offer broad protection
against various influenza virus strains and lessen the...
«We have created a potentially much less expensive approach to making a therapeutic cancer
vaccine that, while
targeting a single tumor antigen, generates an immune response
against multiple antigens.