Thanks to its resemblance to the smallpox virus, researchers were able to use
vaccinia as a vaccine for the disease, eventually leading to its eradication in the late 1970s.
Not exact matches
Lederman, who says he's «obsessed» with Jenner and has been working on a biography of the scientist for 20 years, is convinced that Jenner's original vaccine, now named
vaccinia, was derived from a virus circulating in horses, not cows,
as folklore has it.
In a conversation about one of Evan's earlier
vaccinia papers, Lederman told Evans that he'd love to know whether horsepox still works
as a vaccine, but that he had had trouble getting hold of the virus.
PANVAC - V, which uses the same virus
as the smallpox vaccine, is a live but weakened
vaccinia vaccine (meaning the virus can still multiply) that is given in the arm.
Two other monkeys who were given
vaccinia did better,
as expected, developing no disease at all.
Long used
as a vaccine for smallpox,
vaccinia patiently waits up to 72 hours before busting out.
Late last week, FDA worked with the United States Attorney to ask a court to seize the components of a product that involved the use of
vaccinia virus vaccine
as part of a purported treatment for cancer that FDA believes created the potential for substantial risks to patients.
The Pexa - Vec virus was originally developed by Michael Mastrangelo, MD, and Edmund Lattime, PhD, of Thomas Jefferson University in Philadelphia, who engineered the harmless
vaccinia virus to infect only cancer cells and other rapidly dividing cells,
as well
as to stimulate immune activity, in hopes of boosting the immune response to tumors.
In another report,
vaccinia was used
as a vector vaccine for immunizing Balb / c mice with each of the SARS - CoV structural proteins (N, S, membrane, and envelope) and then challenged with SARS - CoV [21].