Sentences with phrase «vacuole formation»

As blood glucose levels increase, glucose also increases within the aqueous humor, glucose readily diffuses across the lens capsule, an aldose reductase pathway converts glucose to sorbitol, sorbitol accumulates within the lens as it can not diffuse through lens cell membranes, the osmotic gradient increases, water enters the lens and irreversibly changes the lens structure via lens fiber swelling and rupture, vacuole formation, and clinically evident cataract.

Vacuole formation is thought to be a consequence of the uncoupling of exocytosis of zymogens and abnormal intracellular traffi cking of digestive and lysosomal enzymes.

Our results demonstrated that our 3D cell culture device enables a real - time imaging of giant vacuole formation and tracers crossing the cultured endothelial cell monolayer in a controlled experimental condition.

We showed that using a chemical, which can induce the cell into a more relaxed state, can promote giant vacuole formation.

An initial step of GAS - containing autophagosome - like vacuoles formation requires Rab7.

Not exact matches

This is followed by the formation of giant cytoplasmic vacuoles in acinar cells, visible only by electron microscopy.