Sentences with phrase «vaginal microbicides»

These include voluntary male circumcision — now recommended by the World Health Organization and Joint United Nations Programme on HIV / AIDS as a preventive strategy — as well as vaginal microbicides and oral pre-exposure prophylaxis, all of which confer only partial protection against HIV.

Where budgets are limited, they suggest money should be allocated first to increasing male circumcision, then to more frequent HIV screening, use of vaginal microbicides and increasing antiretroviral therapy.

But the most promising candidates — compounds called vaginal microbicides that thwart the virus at the site of infection — have failed repeatedly in clinical trials.

Researchers leading a large, ongoing study in women called VOICE that compares PrEP with pills to a vaginal microbicide plan to revaluate the ethics of continuing to use a placebo control group given the new evidence of oral Truvada's powerful impact.

For 20 years, AIDS researchers have searched for a vaginal microbicide that can block HIV, but they have made little progress.

Not exact matches

McCormack says the data mark the end of the road not just for this vaginal gel but the whole class of microbicides that use nonspecific compounds to prevent HIV - infection.

Janssen GPH will also prioritise work with the International Partnership for Microbicides developing the investigational drug dapivirine for use as a monthly vaginal microbicidal ring designed to prevent sexual transmission of HIV and continue its pact with Drugs for Neglected Diseases initiative for the preclinical research of a reformulated form of flubendazole for lymphatic filariasis (elephantiasis) and onchocerciasis (river blindness), Janssen GPH is also developing a new, chewable formulation of Vermox (mebendazole) that will facilitate treatment of intestinal worms in younger children.