Sentences with phrase «validation studies only»

With PrediXcan, validation studies only need to test a few thousand genes at most, instead of millions of potential single mutations.

Not exact matches

The paper «is a tour de force,» for its labor - intensive validation of concepts that had only been inferred from smaller studies, says molecular pharmacologist Gavril Pasternak of the Memorial Sloan Kettering Cancer Center in New York City.

Diamond is also quick to point out that while the current study shows that COXEN could have been used to predict the most useful drug in many of these cases of advanced ovarian cancer, the actual use of the model will be possible only after validation with a prospective clinical trial.

With functional validation, the only paradigm shift is that more and more journals want to see it before they publish a genetic study.

We regard the proteins that were identified only in one group or differentially abundant between groups, as possible or candidate biomarkers that can be subjected to further analysis in validation and verification studies.

This is very encouraging for the future application of measurements from sea - going spectral radiometers, as instruments not only for the validation of satellite - derived SST but also for studying the physics of the ocean skin temperature layer.

The only specific policies that I have advocated are (1) that scientists be required to archive their data and methods; (2) that proxies used in multiproxy studies be brought up to date to permit validation against the warm 1990s; (3) that disclosure and due diligence practices in climate science be improved.

More accurate and reliable precipitation data would be invaluable, not only for the study of climate trends and variability, but also as inputs to hydrological and ecological models and for model validation, characterization of extreme events, and flood and drought forecasting.

Add to that the fact that some of the most widely cited validation studies (eg Mann) appear to have question marks over their methodology, and I believe it is only rational to remain sceptical, at least as regards the extent of AGW.

To date these remain the only large - scale driver risk assessment validation studies of their kind — conducted by applied university - level research experts with up to 26,000 participants.

In the validation study (Olson, Gorall & Tiesel, 2007), scale reliabilities were reported to be acceptable for research purposes and applicable for clinical purposes only if combined with other methods of assessment, ranging from alpha =.77 to alpha =.89 (Olson et al., 2007).

According to the developers of this instrument, it has been used extensively in practice but validation studies of this instrument have only been published in special populations at present.34 35 The young adult version will also be used to assess psychopathology in those aged 18 years and over in the current study to allow continuity of measurement across the full sample.

Second, we reported higher Cronbach's α reliability scores than most preschool and school - aged validation studies, 10,15 with only the preschool peer problems subscale failing to meet the α > 0.70 criteria for satisfactory internal reliability.

The previous studies were based in The Netherlands, 15 Spain, 16 Germany, 17 and Japan.18 Each supported a 5 - factor configuration.15 — 18 Table 1 presents preschool internal reliabilities compared with the school - age SDQ.10 Only 1 preschool validation study used McDonald's ω coefficient to estimate internal reliability.