Depakote / depakane /
valproate causes shortages in l - carnatine, folate, vitamin E and sometimes selenium, and the low folate causes anemia — specifically (in me) low hematocrit or hemoglobin levels, rarely both.
Morland C, Nordengen K, Gundersen V (2012)
Valproate causes reduction of the excitatory amino acid aspartate in nerve terminals Neurosci Lett, 527 (2), 100 - 4 PubMed 22963924