Sentences with phrase «valproate in»

Efficacy of aripiprazole versus placebo as adjuncts to lithium or valproate in relapse prevention of manic or mixed episodes in bipolar I patients stratified by index manic or mixed episode

Of those children, 64 were exposed to valproate in utero, 44 to lamotrigine, 76 to carbamazepine, and 65 to other epilepsy drugs or combinations of drugs.

Valproate in the treatment of acute mania.

Not exact matches

The study helps determine the effects of CBD in combination with common AEDs, including carbamazepine, valproate, levetiracetam, clobazam and lacosamide.

The seizure drug valproate and capsaicin cream, which were considered probably effective in the 2011 AAN guideline, were ineffective in this meta - analysis.

The researchers also evaluated negative symptoms in 43 patients with bipolar disorder, about half of whom were treated with valproate.

The authors conclude that valproate may be effective for treating negative symptoms in psychiatric patients with two copies of the «Val» variant of the COMT gene, which breaks down dopamine in the brain.

Of these 171 women, 42 had taken levetiracetam, 27 had taken topirimate and 47 had taken valproate while pregnant — an additional control group of women with similarly - aged children who had not taken any antiepileptic drug while pregnant was also included in the study.

Among those patients who were being treated with valproate (approximately one - third of the schizophrenia patients), negative symptoms were more severe in those with the Met / Met gene than in those with the Val / Val gene.

In the roughly 40 percent of patients with this genotype, higher levels of proline (a neuromodulator that is increased by valproate), correlated with fewer negative symptoms.

In patients who have a «Met» variant of COMT, rising levels of proline appeared to do the exact opposite: these patients had more or worse negative symptoms, and the symptoms did not improve with valproate.

Valproate, one of the most commonly prescribed antiepileptic medications, has been associated in the past with birth defects and developmental problems.

Joseph F. Hayes, M.Sc., M.B.Ch.B., of University College London, England, and coauthors compared rates of self - harm, unintentional injury and suicide deaths in patients prescribed lithium, valproate sodium, olanzapine or quetiapine using a large database of electronic health records in the United Kingdom.

A common mood - stabilizing drug, valproate, is found to control manic - like behavior induced in mice with an extra copy of a gene called SHANK3

Valproate increases pro-apoptotic efficacy of chemotherapeutic regimen in small cell lung cancer.

Study of the effect of valproate on pulmonary cancer cells, in combination with chemotherapy agents.

Morland C, Nordengen K, Gundersen V (2012) Valproate causes reduction of the excitatory amino acid aspartate in nerve terminals Neurosci Lett, 527 (2), 100 - 4 PubMed 22963924

Compared to children whose mothers did not have epilepsy, the risk of autism was seven times higher in those with valproate exposure.

Alycia Halladay, PhD, the director of research for environmental sciences at Autism Speaks, an advocacy group that raises money for biomedical research, says the study «adds to the growing literature that in utero exposure to [valproate] may be one possible risk factor for autism.»

'' [Then] research can turn to the ways in which women who can not stop or reduce [valproate] treatment while pregnant can ameliorate the risk of birth defects,» Halladay says.

(There was one case of autism each in children exposed to lamotrigine, phenytoin, and a combination of lamotrigine and valproate.)

By Kate Stinchfield MONDAY, Dec. 1, 2008 (Health.com)-- Pregnant women who take the epilepsy drug valproate may be more likely to have a child with autism than those who don't take the seizure - controlling drug, according to a study published Monday in the journal Neurology.

First line drugs used in the treatment of a migraine include propranolol, topiramate, Divalproex / sodium valproate, and metoprolol.

Ketogenic diet - induced toxicity of the anticonvulsant medication sodium valproate has been reported (30) however these treatments can be used together without problem in most cases (31).

Carnitine does not improve weight loss outcomes in valproate - treated bipolar patients consuming an energy - restricted, low - fat diet.

Depakote / depakane / valproate causes shortages in l - carnatine, folate, vitamin E and sometimes selenium, and the low folate causes anemia — specifically (in me) low hematocrit or hemoglobin levels, rarely both.

Valproate reduces alcohol consumption in people with comorbid alcohol dependency and bipolar disorder