Dario C. Altieri, M.D., Wistar's President and CEO and lead author of the study, and colleagues showed how the activation of this pathway leads to an unfavorable prognosis for patients with gliomas — a type of brain tumor — and how the pathway could be
a valuable therapeutic target in cancer.
When STAT3 was knocked out in a mouse model, researchers observed increased T - cell immune responses, suggesting
a valuable therapeutic target.
Not exact matches
It could be suggested that Cyclin D1 protein may be a
valuable prognostic marker in IDC and can be
targeted in the future
therapeutic approaches.
By comparing all of the genes that are active in disease and normal tissue, one can get
valuable information on new pathways and potential
therapeutic targets.
This work will provide
valuable insight into the role of microglia within canine DM disease progression and could identify key areas for the development of microglia - specific
therapeutic targets that could slow or halt further disease progression.