Sentences with phrase «valve leaflets»

They identified that cells from one of the three distinct layers in an aortic valve leaflet, the lamina fibrosa, had the highest propensity to calcify.

On video 1 and 4 we can see the slight thickening and prolapsed mitral valve leaflets, so I supposed that the dog had degeneration of the mitral valve.

There was some suggestion that the incidence of mini-stroke — called transient ischemic attacks — but not full blown strokes, could be increased by untreated valve leaflet clots but this was inconclusive and requires further study.

Once the new valve is expanded, it pushes the old valve leaflets out of the way and the tissue in the replacement valve takes over the job of regulating blood flow.

Today in Circulation, the journal of the American Heart Association, Vanderbilt University researchers published findings that the drug — a monoclonal antibody known as SYN0012 — shows promise in keeping heart valve leaflets supple.

However, in some patients whose hearts have uncommon structures, such as unusually large valve leaflets or small aortic roots, the large leaflets block the flow of blood to the coronary arteries as the new valve's scaffolding opens.

The top arrow points to a normal valve leaflet.

The bottom arrow points to a thickened valve leaflet, which could be the result of chronic bacteria from the mouth.

This treatment involves the passage under general anesthesia of special catheters which when an attached balloon is inflated, tears the restricted valve leaflets.

Inflammatory markers were identified in tissue samples from all disease stages in the aortic valve leaflets.

Although current mitral valve interventions delivered via a small incision through the skin could be a viable alternative treatment, this strategy benefits only a highly selective group of patients who have mitral valve leaflets (which are flaps that seal the valve) of a particular shape.

Aortic stenosis is a common heart problem caused by a narrowing of the heart's aortic valve due to excessive calcium deposited on the valve leaflets.

Said Hasan Jilaihawi, MD, director of Interventional Cardiology Imaging at the Cedars Sinai Heart Institute, «Our study also shows that the novel technique of four - dimensional high resolution CT is superior to routinely used transthoracic cardiac echocardiography for the detection of these valve leaflet clots.»

Makkar began the study when a high - resolution imaging study of one of the patients in a clinical trial who had stroke showed clot formation on the aortic valve leaflets that open and close to regulate the flow of blood.

«The valve leaflets can become thick and lose their support structures over the years and the valve function gets progressively worse,» said Dr. Stephen Little, director of the Valve Clinic at Houston Methodist Hospital.

This degeneration results in thickening and elongation of the valve leaflets, which affects the ability of the valves to close properly.

It is also seen more commonly in small breed dogs with other disorders of cartilage formation and growth, suggesting that the mechanism may involve abnormal growth or degeneration of the connective tissue components of the valve leaflets.

Symptoms: The symptoms of MVD vary depending on the severity of degeneration of the valve leaflets.

Approximately 60 % of affected dogs have degeneration of the mitral valve, 30 % have lesions in both the tricuspid and mitral valve leaflets, and 10 % have only tricuspid valve disease.

The mitral valve problem is caused by endocardiosis, polysaccharide deposits in the valve leaflets.

Heart murmurs are «swooshing» sounds created by turbulent blood flow and are most commonly associated with diseases that affect the heart valves such as degenerative valve disease, AV valve dysplasia, pulmonic stenosis however, disease that do not primarily affect the valves such as dilated cardiomyopathy may secondarily cause a murmur by stretching apart the valve leaflets causing them to leak as the heart enlarges.