Sentences with phrase «variable penetrance»

However it gets much more complicated (that old variable penetrance) as hounds have been documented to be normal until age 9 and then develop afib.

In contrast, an autosomal dominant mode of inheritance with a high degree of penetrance has been suggested for the pulverulent (dust - like) form of cataract observed in the Norwegian Buhund [116] and autosomal dominant with variable penetrance has been suggested for inherited posterior polar subcapsular cataracts in the Labrador and Golden retriever [117], although current anecdotal evidence indicates that in the Labrador cataracts could also be inherited as an autosomal recessive trait.

(ref) The problem is that some dogs that carry these genes will never develop the disease (incomplete or variable penetrance) while others that appear free of those genes develop cardiomyopathy (DCM) all the same.

ARVC is a disease of variable penetrance.

There is likely to be a continuous range of genes with variable penetrance all of which probably interact with other genes and with the environment.

Not exact matches

Heteroallelic combinations between four psq alleles (fs1, 0115, KG02404, and rev12) and the rum mutation gave rise to embryonic terminal defects of variable strength and penetrance (Figure 2, G — I; Table S1).