In addition to our computational work, we run a small wetlab where we use CRISPR - Cas genome editing in human cell lines to obtain a deeper understanding of how genetic
variants affect the cell.
Not exact matches
But in the genetically modified
cells that carried the genetic
variants of the tribble protein, several proteins that are critical to the «docking» process were being
affected.
New common
variants affecting susceptibility to basal
cell carcinoma.
We show that the c. 2737C > T
variant does not trigger nonsense - mediated decay of the ZSWIM6 mRNA in
affected individual - derived
cells.