Because of its rapid rise, the gene becomes fixed in the genome with less
variation than a gene that spread more slowly and was subject to the shuffling effects of recombination.
Not exact matches
Based on the core principles of behavioral genetics, if genetics explain
variations in distrust and trust behaviors, then identical twins should behave more similarly to each other
than fraternal twins, since the
genes of identical twins are shared, while the
genes of fraternal twins are only imperfectly correlated, Reimann said.
More to the point, your health, your life span — and even some of your actions — may have more to do with the genetic
variation in those microorganisms you host
than they do with your own
genes.
In all, the study included the data of more
than 23,000 people to show that approximately 12 percent of a person's
variation in delay discounting can be attributed to genetics — not a single
gene, but numerous genetic variants that also influence several other psychiatric and behavioral traits.
They discovered that genetic
variation influencing a person's risk for multiple sclerosis, rheumatoid arthritis, and type 1diabetes is more likely to control
gene activity in T cells
than in monocytes.
«All three predictions were met: facial traits are more variable and less correlated
than other traits, and the
genes that underlie them show higher levels of
variation,» Nachman said.
The scientists estimate that these
gene variations were able to persist in Neanderthals because Neanderthals had a much smaller population size
than humans.
Researchers report that one tiny
variation in the sequence of a
gene may cause some people to be more impaired by traumatic brain injury (TBI)
than others with comparable wounds.
By studying rare «copy number
variations,» which are individual errant insertions or deletions of DNA segments (each of which occur in less
than one percent of the population), researchers discovered a new cluster of
genes that are affected in some autistic individuals as well as a number of mutations that were present in autistic children but not their parents.
Although bacteria have a seemingly limitless capacity to alter their
genes by swapping bits of DNA between strains, this mechanism doesn't seem enough to account for the swift pace of change and the high variability of E. coli and other strains.Thomas Cebula of the U.S. Food and Drug Administration (FDA) wondered if this rapid evolution is being driven by microbes capable of much faster -
than - normal
variation.
Analysing
variations in folk tales using genetic techniques shows that people swap
genes more readily
than stories, giving clues to how cultures evolve
Patients with a particular inherited
variation in the
gene IFITM3 were more
than twice as likely to develop severe, life - threatening flu symptoms as those who carried the protective version of the
gene.
So when Drake and his colleagues measured the RNA levels — a direct link to how much of a
gene is being produced — in the
genes of 334 mice, he didn't expect to find more
than a few
variations that might help explain why males and females have such different rates of cardiovascular disease and diabetes or why they react differently to certain drugs.
When the team looked at the chromosomes of more
than 1000 people from populations around the world, they concluded that the prevalence of two of these
variations was due to an evolutionary balancing act that had kept them in the
gene pool for as long as 500,000 years.
They showed how
variations in breast cancer cells» RNA, the molecule that decodes
genes and produces proteins, helps the cancer to evolve more quickly
than previously thought.
The new work, published October 20 in PNAS, shows how
variations in breast cancer cells» RNA, the molecule that decodes
genes and produces proteins, helps the cancer to evolve more quickly
than previously thought.
They found that individuals with the
variation on the RASGRF - 2
gene drank more frequently at the age of 16
than those with no
variation on the
gene.
With 20 contingency
genes, a bacterium would have a repertoire of more
than a million possible
variations.
As an example, skeletal malformations and dysplasias, often detected through routine prenatal ultrasound examination, constitute a phenotypic finding in more
than 300 syndromic and non-syndromic disorders and their genetic etiology may be due to a wide variety of genetic aberrations, ranging from copy number
variations to single
gene mutations.
A
variation of the
gene - editing technique can more precisely and efficiently downregulate the expression of target
genes than traditional CRISPR / Cas9.
By utilizing paired genome - wide high - throughput DNA sequencing (DNA - seq) with RNA - seq, we found that
gene dosage, at the level of individual
genes or chromosomal «somy» (a general term covering disomy, trisomy, tetrasomy, etc.), accounted for greater
than 85 % of total
gene expression
variation in
genes with a 2-fold or greater change in expression.
The researchers also determined that rare inherited
gene variations — those found in less
than 5 % of people — contribute another 3 % of autism population risk.
We find that Polycomb repressive complex - active
genes have greater cell - to - cell
variation in expression
than active
genes, and these results are validated by knockout experiments.
Variations in a particular
gene may help explain why some people appear more youthful
than others, researchers say.
However, the good news is that according to the 2011 study even moderate physical activity such as walking is able to reduce the negative influence of this obesity - related
gene variation by more
than 25 %!
However, if «feeling worse» lasts more
than few days, this could be due to overmethylation, other
gene variations, or a sensitivity to the supplements; and the supplements should be discontinued.
The increased power provided by looking for specific
gene candidate
variations rather
than linked markers will aid the identification of epilepsy risk factors, perhaps leading to development of DNA tests to enable breeders to select against such risk factors.
Related to this question, recent research suggests that particular polymorphisms, often those linked to risk for pathology, make the individual more susceptible to be influenced by parenting and other experiences.24 - 26 For example, children carrying the 7 - repeat
variation of the DRD4 appear to benefit more from interventions directed to prevent behaviour problems
than those carrying other
variations of the
gene.24 Nonetheless, further research is needed on how and to what extent EC skills may be influenced by the interplay between constitution and experience.