I've seen headless NPCs, gotten stuck on
various stairs, had it crash several times, been unable to draw my sword, come out of quick - travel into a fight without my weapons equipped, lost my horse during fast travel, seen NPCs do a variety of
daft things, had quests fail to trigger correctly and a bunch of other
things.
The
various stages that you will play through are designed to perfection, the only
thing to blame for failure will be yourself, and I often beat myself up for
daft mistakes rather than blaming poor design.