Sentences with phrase «various model animals»

Not exact matches

PPAR gamma agonists have shown strong potential in animal models related to the various phenotypes associated with X-ALD.

After applying it to the various species» calls, the researchers report this week in the Proceedings of the Royal Society B that they found no evidence that animals» vocalizations are restricted as the model would suggest.

In past studies to develop a new animal model for the brain events that support motor development, neurophysiologist Martin Garwicz of Lund University in Sweden and his colleagues discovered that the schedules by which ferrets and rats acquire various motor skills, such as crawling and walking, are strikingly similar to each other; the progress simply happens faster for rats.

The researchers are now working to understand how lncRNAs work in various animal models, and how their dysfunction may promote disease.

«We know from animal models that there are critical periods during early development when cells are rapidly dividing and forming the circuitry through which cells will communicate with each other to form various tissues of the body,» said Retha Newbold, a reproductive biologist at the National Institute of Environmental Health Sciences in North Carolina.

To this end, the researchers selected an approach based on machine learning that is often used in nature and wildlife conservation to develop models for the distribution of various species of plants and animals.

In various talks, interviews and articles, he suggested that a mathematical brain model would deliver such fundamental breakthroughs as simulation - driven drug discovery, the replacement of certain kinds of animal experiments and a better understanding of disorders such as Alzheimer's.

Some methods focus on animal models enabling to compare the impact of various monitored flora on the phenotype or to measure this impact according the genotype of modified animals.

Understanding cattle movement patterns as well as the connectivity of the various sectors of the U.S. cattle industry and incorporating these in the models would allow USDA Animal Plant Health Inspection Service (APHIS) Veterinary Services (VS) to develop more effective regulations and control strategies for various animal diseases, including boviAnimal Plant Health Inspection Service (APHIS) Veterinary Services (VS) to develop more effective regulations and control strategies for various animal diseases, including bovianimal diseases, including bovine TB.

CELPHEDIA WP1 workgroup gathers experts using CRISPR / Cas9 system in various animal models including mouse, rat, zebrafish and drosophila.

Once we have a better mechanistic understanding of the factors that drive selective modulation of GABAB receptors, we can assess how these new compounds affect various behaviors in animal models.

Additional protocols are currently under development to measure SMN protein in other tissues and biofluids, as well as in various tissues from animal models.

Objective: Exposure to phencyclidine (PCP) has been used as an inducing condition in various animal models of schizophrenia.

As one of the three initial cores established when the Buck Institute was founded, the Genomics Core has played a vital role in helping shape investigations in the basic molecular biology of aging, from assisting in the investigation of how specific drugs can extend lifespan in simple model organisms such as the nematode C. elegans, to facilitating studies in various animal models of age - related disease.

The main research activity (located in central Paris and vicinity at Orsay) regroups to date 16 technology platforms and services offering state ‐ of ‐ the - art expertise and equipment from small molecule chemistry to omcs, super-resolution microscopy, sophisticated radiation sources and various animal models, including xenografts directly derived from patients, in order to promote the best environment and support for research activities.

Transplantations of various stem cells or their progeny have repeatedly improved cardiac performance in animal models of myocardial injury; however, the benefits observed in clinical trials have been generally less consistent.

Alternative animal replacement models are of great value in studying host - pathogen interaction and for quick screening of various pathogenic strains.

The endocannabinoid system regulates energy homeostasis through G protein — coupled cannabinoid - 1 receptors5, 6 located in the central nervous system and in various peripheral tissues, including adipose tissue, muscle, the gastrointestinal tract, and the liver.7 While peripheral cannabinoid - 1 receptor activation decreases adiponectin production in adipocytes, 8 central cannabinoid - 1 receptor activation in preclinical studies stimulates eating, decreases muscle, and stimulates hepatic and adipose tissue lipogenic pathways in animal models of obesity.9 In genetic and diet - induced obesity, rimonabant, a selective cannabinoid - 1 receptor blocker, reduces overactivation of the central8, 10 and peripheral11, 12 endocannabinoid system8, 10,13 and prevents weight gain and associated metabolic disorders, thus revealing a novel strategy for the treatment of obesity and related cardiometabolic disorders.

Animal studies, mainly models which test the impact of aerobic exercise, indicate that various mechanisms are responsible for these effects.

Multiple studies show that the catechin compounds found in green tea can have various protecting effects on neurons in test tubes and animals models, potentially lowering the risk of disease like Alzheimer's and Parkinson's.

Finally, we estimated the effect of substituting 3 % of energy from plant protein for an equivalent amount of animal protein from various sources, including processed and unprocessed red meat, poultry, fish, egg, and dairy, by simultaneously including these protein items as continuous variables in the multivariable model.

We used a nutrient density model with adjustment for total energy intake and the percentage of energy from various fats (saturated, polyunsaturated, monounsaturated, and trans - fat).16 Thus, the coefficient for animal and plant protein reflects the substitution effect of an equal amount of energy from protein for carbohydrate.

Multiple studies show that the catechin compounds in green tea can have various protective effects on neurons in test tubes and animal models, potentially lowering the risk of Alzheimer's and Parkinson's (28, 29, 30).

Since Animal Crossing: Pocket Camp is a smartphone game, with micro-transactions as business model, it's going to get various events and content updates on a regular basis.

In this lesson, students will learn to make and interpret scale models and practice using the metric system for measurement by discovering the relative sizes of various large plants and animals.

Impact of the study on quality of care: Results may serve as a model for obtaining information critical to developing veterinary continuing education and public outreach programs for animal owners for various diseases.

Character models look good, as do the various animals that share the island with you.

Binary models infuse our thinking at every level in society, as life is constantly split into various dichotomies of rich / poor, traditional / contemporary, animal / human, and so on ad infinitum.

Therefore, various nontraditional animal models, which display pair bond formation — including marmosets (Callithrix penicillata), titi monkeys (Callicebus cupreus), California mice (Peromyscus californicus), and prairie voles (Microtus ochrogaster)-- have emerged as better alternative animal models to study the neural correlates of pair bond formation (Carter et al., 1995; Bester - Meredith et al., 1999; Bales et al., 2007; de Jong et al., 2009; Smith et al., 2010).