Sentences with phrase «various phenotypic changes»
Not exact matches
The approach to target validation utilizes RNAi, CRISPR, and ORF expression platforms to genetically perturb candidate target gene expression in relevant cancer cell lines, and then profile the resulting phenotypic changes with regard to their effect on various biochemical pathways.
https://www.broadinstitute.org/
The significant changes reinforced the impact of the genetic background to various phenotypic analysis, even using nearly divergent substrains.