This review will highlight commonly used dietary factors able to influence LDL - C and atherosclerosis in
various rodent models, as well as some of the potential benefits and drawbacks associated with using these models for disease induction.
Since the presence of phytoestrogen containing sources (i.e. soy protein and isolated isoflavones) has been found to influence atherosclerosis and lipoprotein metabolism in
various rodent models (7 - 13), the use of purified Western - type diets provides a clean «reagent» for inducing this disease.
Qualified candidate must be a motivated, talented and disciplined scientist having excellent expertise in behaviorally assessing
various rodent models of neurodegenerative disease.
Not exact matches
During panel discussions Sept. 18 at 6, 7 and 8 a.m. PDT (9, 10 and 11 a.m. EDT), scientists and researchers will discuss the
various science and research studies, including RapidScat, 3 - D printing in Zero - G, technology to measure bone density, and
model organism research using
rodents, fruit flies and plants.
NASA will host a prelaunch panel discussion at 8 a.m. PDT Sept. 18, at the agency's Kennedy Space Center in Florida, featuring scientists and researchers who will discuss
various science and research studies, including the four Ames - supported payloads to study
model organism research using yeast,
rodents, fruit flies and plants.
In
rodents, ketogenic diets reduce reactive oxygen species in the brain34 and reduce central inflammation and reactive oxygen species in a
model of multiple sclerosis.35 Two clinical papers have found that ketogenic diet feeding of 12 weeks to 6 months reduced signs of liver inflammation in obese patients with nonalcoholic fatty liver disease (in addition to improving
various other physiological and biochemical variables).36, 37 Unfortunately, basic research into non-alcoholic fatty liver disease has been hampered by species differences between mice and humans in their hepatic reaction to ketogenic diets.38
Furthermore, it is suggested that calorie restriction can display beneficial effects in
rodent models of
various neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's disease (5).