Sentences with phrase «vascular endothelial»

Other progress against the wet form of the disease has come through the use of drugs that target vascular endothelial growth factor.

The list includes platelet - derived growth factors (PDGF), ß - thromboglobulin, fibroblast growth factor, insulin - like growth factor 1, epidermal growth factor, and vascular endothelial growth factor.

Vascular endothelial growth factor concentrations in body cavity effusions in dogs.

Plasma vascular endothelial growth factor (VEGF) concentrations in healthy dogs and dogs with hemangiosarcoma.

In this proposal we set out to utilize our canine - derived scFv phage display platform technology to isolate canine antibody fragments that bind and neutralize Vascular Endothelial Growth Factor (VEGF).

The use of targeting antibodies against vascular endothelial growth factor (VEGF), a protein that promotes tumor growth and spread, plus chemotherapy has prolonged disease free survival in several different tumor types in man.

It is an incurable tumor of cells that line blood vessels, called vascular endothelial cells.

One of these growth factors is vascular endothelial growth factor - A or VEGF, which acts by binding specific receptors on the hemangiosarcoma cells.

Bartonella is a gram - negative, aerobic bacilli that infects primarily the erythrocytes and vascular endothelial cells of its hosts.

However, the effect of SMR on arterial stiffness and vascular endothelial function using a foam roller is unknown.

However, the effect of SMR using a foam roller on arterial stiffness and vascular endothelial function remains unknown.

Stiffness in large elastic and muscular arteries is influenced by vascular endothelial function (29).

Exercise training leads to the formation of new capillaries in a process called angiogenesis, mediated through the vascular endothelial growth factor (VEGF) signaling pathway (Gavin, 2009).

Vascular endothelial cells play an important role in the regulation of vascular activity by producing vasoactive substances such as NO.

This study investigates the acute effect of SMR using a foam roller on arterial stiffness and vascular endothelial function.

These results indicate that SMR using a foam roller reduces arterial stiffness and improves vascular endothelial function.

One major internal contributor to cancer is called «vascular endothelial growth factor,» or VEGF.

Lin, L., et al. «Protective effect of gypenosides against oxidative stress in phagocytes, vascular endothelial cells and liver microsomes,» Cancer Biotherapy, 8 (3): 263 - 72, 1993.

Alpha - lipoic Acid Improves Vascular Endothelial Function in Patients with Type 2 Diabetes: A Placebo - controlled Randomized Trial Eur J Clin Invest.

The patients treated with placebo experienced no change in FBF while the patients treated with ALA experienced improved vascular endothelial function.

In conclusion, alpha - lipoic acid may reduce the risk of vascular endothelial dysfunction.

Vascular endothelial dysfunction promotes vasoconstriction and favors platelet aggregation, white blood cell adhesion, and smooth muscle cell proliferation.

Linoleic acid induces proinflammatory events in vascular endothelial cells via activation of PI3K / Akt and ERK1 / 2 signaling

The primary factor is inflammation and health of the vascular endothelial cells.

Researchers report that curcumin reduces all pro-inflammatory molecules in cartilage cells and in membranes that line the joints, among them tumor necrosis factor — which destroys joint cartilage — and vascular endothelial growth factor, which promotes excessive growth of blood vessels in inflamed joints.

Ishikado, A. Sono, Y. Matsumoto, M. Robida - Stubbs, S. Okuno, A. Goto, M. King, G. Blackwell, K. Makinoa, T. Willow bark extract increases antioxidant enzymes and reduces oxidative stress through activation of Nrf2 in vascular endothelial cells and Caenorhabditis elegans.

At the same time, the protein Vascular Endothelial Growth Factor (VEGF) stimulates blood supply for the damaged tissue, Fibroblast Growth Factor - 2 (FGF - 2) stimulates the damaged cells to grow and reproduce themselves, Transforming Growth Factor - beta (TGF - beta) stimulates cartilage to grow, and Stem Cell Factor (SCF) stimulates your native inactive stem cells to become activated and assist in the repair of the damaged tissue.

This review describes the results of studies exploring the putative effects of coffee components, especially in protecting vascular endothelial function and preventing metabolic syndrome.

Of note, in systemic and pulmonary vascular endothelial cells, smooth muscle cells, and fibroblasts, 2 - CH30 E2 exerts stronger anti-mitotic effects than estradiol itself.

[6] Another natural isoflavinoid, 4 - O - methyl alpinumisoflavone, isolated from the tropical rainforest tree, Lonchocarpus glabrescens, could inhibit HIF - 1 activation and hypoxic induction of HIF - 1 target genes (CDKN1A, GLUT - 1, and vascular endothelial growth factor (VEGF)-RRB-.

«Flavonoids and Vitamin E Reduce the Release of the Angiogenic Peptide Vascular Endothelial Growth Factor from Human Tumor Cells».

-- Naringin is an inhibitor of vascular endothelial growth factor (VEGF) release, which causes angiogenesis (formation of new blood vessels)(4).

One class of drugs, called vascular endothelial growth factor inhibitors, for example, is designed to thwart the growth of abnormal blood vessels in the eye.

In 1996, for instance, Semenza demonstrated that HIF - 1 activates the gene for a key participant in blood - vessel formation, vascular endothelial growth factor (VEGF).

This activates the mast cells in these organs so that they undergo degranulation, releasing ready - made proteases such as chymase and tryptase, and synthesizing inflammatory mediators (leukotrienes and vascular endothelial cell growth factor [VEGF]-RRB-.

Adults with advanced renal cell carcinoma after targeted therapy against vascular endothelial growth factor (VEGF)

Furthermore, ASCs secreted high levels of vascular endothelial growth factor (VEGF) into the wound site, thereby promoting accelerated angiogenesis and encouraging higher levels of wound healing.

In a report published online in Diabetes, the authors showed that RUNX1 was upregulated in vascular endothelial cells obtained from fibrovascular membranes in PDR patients.

Under hypoxic conditions activates the transcription of over 40 genes, including, erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia.

Interferon -LCB- alpha -RCB- but Not Interleukin 12 Activates STAT4 Signaling in Human Vascular Endothelial Cells

Sep. 13, 2016 — High levels of blood markers for vascular endothelial dysfunction were associated with longer periods of confusion in ICU patients, Vanderbilt researchers have discovered.

Modulation of T cell and B cell interactions with vascular endothelial cells by antibodies, complement, and platelets

The drug, marketed as Lucentis, targets a molecule called vascular endothelial growth factor (VEGF), a key player in the growth of blood vessels.

The researchers found that, when stimulated by insulin, diabetic fibroblasts produced less of the VEGF (vascular endothelial growth factor) signaling protein, a key player in boosting the growth of blood vessel cells, than normal fibroblasts did.

Vascular endothelial growth factor receptor, also called VEGFR, is a biomarker found in certain patients with lung cancer.

So what do vascular endothelial cells and ACC have to do with one another?

However, recent small short - term studies have revealed the visual benefits of eye injections of medications that block a chemical signal that stimulates blood vessel growth, known as vascular endothelial growth factor (VEGF).

From these cell based and clinical studies, we have developed important mechanistic ideas such as activation of protein kinase C, the role of vascular endothelial growth factor (VEGF) and selective insulin resistance as some of the basic mechanisms for the pathogenesis of diabetic microvascular and cardiovascular diseases which are now widely studied by multiple laboratories.

Vascular endothelial growth factor (VEGF) expressed by neural progenitor cells (NPCs)(cyan) stimulates the growth of blood vessels (red) in the mouse embryonic hindbrain, and provides regulatory factors to promote the self - renewal of neural progenitors.

For the analysis of mRNA levels for asparagine synthetase (ASNS), CHOP (CCAAT / enhancer - binding protein homologous protein), vascular endothelial growth factor (VEGF), glucose transporter 1 (Slc2a1) and monocarboxylate transporter 4 (Slc16a3), RT - PCR as well as qPCR were used.