Sentences with phrase «vascular endothelium»
The phrase "vascular endothelium" refers to the lining of the blood vessels. It is a thin layer of cells that cover the inner surface of blood vessels, such as arteries and veins. The vascular endothelium plays a crucial role in regulating blood flow, controlling the passage of substances into and out of the blood, and maintaining the health and function of blood vessels. Full definition
In the process of blood vessel differentiation, the function of the protein ETS variant 2 (ETV2), which determines the differentiation into vascular endothelium, was first induced within 6 hours of differentiation stimulation.
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It also induces the secretion of vascular endothelium growth factor (VEGF), which leads to the increased growth of blood vessels and vascular permeability in inflammation (3).
A study on postmenopausal women found that oral curcumin supplementation, in conjunction with an exercise regimen, helped to improve vascular endothelium function.
In this case, disruption of stable vascular endothelium disrupts this dormant niche and encourages the formation of a microenvironment that sparks micrometastatic outgrowth.»
Until now, no dengue viral proteins have been linked to vascular endothelium permeability (that is, vascular leakage).
We show that TNF administration damaged the liver vascular endothelium and induced phosphorylated mixed lineage kinase domain - like (phospho - MLKL) reactivity in endothelial cells isolated from TNF / zVAD - treated WT, but not Ripk1D138N / D138N, mice.
Intriguingly, these cells, which resemble perivascular macrophages or so - called «Mato Cells» in mammals, appear to emerge by transdifferentiation from endothelium of the optic choroidal vascular plexus, and as such would represent the first described perivascular cell population in the brain derived from vascular endothelium.
Michael Gustave Poulos, PhD Weill Cornell Medical College New York, NY Aging Vascular Endothelium Modulate Hematopoietic Stem Cell Activity
In September of 2008, Journal of Nutrition published an Italian university study investigating the therapeutic potential of chocolate and found that, «Flavanols from chocolate appear to increase nitric oxide bioavailability, protect vascular endothelium, and decrease cardiovascular disease (CVD) risk factors....
It is believed that a healthy vascular endothelium is resistant to bacterial infection.
At 48 hours, after differentiation into vascular endothelium was determined, a system of transcription was established in which genes unique to vascular endothelial differentiation were induced.
In addition, when these transcription factors lose their function, terminal differentiation into the vascular endothelium (completion of differentiation) is completely suppressed, and genes that are key to differentiation into vascular endothelial cells as well as transcription factors that maintain the undifferentiated state are adversely induced.
Furthermore, an examination of the histone code revealed that the regulatory genomic region of the transcription factors (ETS / GATA / SOX) was found to have gradually switched from a «brake histone mark,» which suppresses transcription, to an «accelerator histone mark,» which activates transcription, while in the process of differentiating into the vascular endothelium.
The inducible cell adhesion molecules E-selectin and VCAM - 1 are differentially expressed along the surface of the vascular endothelium and particularly enriched at the level of the postcapillary venule (17), where E-selectin mediates leukocyte and VCAM - 1, lymphocyte recruitment processes (14).
We have developed liposomal systems able to deliver siRNA molecules to a variety of organs and cell types, including liver, lung and vascular endothelium.
His basic research interests include inflammation and innate immunity, receptor - mediated signaling in neutrophils and vascular endothelium, lipid biochemistry, and Transfusion Medicine with emphasis on transfusion - related acute lung injury (TRALI) and resuscitation following injury.
Curcumin is believed to support healthy function of the vascular endothelium, which could support heart health.
As the human body ages, it has less function in its vascular endothelium (the lining of blood vessels).
Compression might distort the vascular endothelium, which could trigger the release of vasodilator substances such as NO (28).
Canine infectious hepatitis is caused by an adenovirus that affects the liver, kidneys, eyes and vascular endothelium.