F In addition to LOX - 1 mediated vascular inflammation, oxLDL / LOX -1 internalization triggers endothelial /
vascular smooth muscle cell dysfunction, apoptosis, cellular senescence, or osteoblastic differentiation.
Vitamin D also can
suppress vascular smooth muscle cell proliferation, activation of garbage - eating macrophages and calcification formation, all of which can thicken blood vessel walls and hinder flexibility.
The researchers went on to demonstrate that SHP - 1 is reduced in
mouse vascular smooth muscle cells primarily by the high levels of lipids in the blood associated with diabetes and related conditions, rather than the high levels of glucose also present in those conditions.
Lymphocytes influence intracranial aneurysm formation and rupture: role of extracellular matrix remodeling and phenotypic modulation
of vascular smooth muscle cells.
Mechanotransduction The effects of extracellular matrix stiffening on endothelial cell health Cynthia Reinhart - King, Cornell University The effects of membrane cholesterol and extracellular matrix elasticity on
vascular smooth muscle cell mechanics and migration Zhongkui Hong, University of South Dakota
FEBS, 2 Jan 2 1998, 421 (1): 19 - 22 «High concentration of glucose causes impairment of the function of the glutathione redox cycle in
human vascular smooth muscle cells»
In superior cervical ganglions and
cerebral vascular smooth muscle cells, inhibits voltage-gated Ca (2 +) channels in a constitutive, as well as agonist - dependent manner (By similarity).
In addition to LOX - 1 mediated vascular inflammation, oxLDL / LOX -1 internalization triggers endothelial /
vascular smooth muscle cell dysfunction, apoptosis, cellular senescence, or osteoblastic differentiation.
We show that
vascular smooth muscle cells and blood vessels from estrogen receptor β (ERβ)-- deficient mice exhibit multiple functional abnormalities.
ADRCs are a combination of cell types, such as adult stem cells, vascular endothelial cells, and
vascular smooth muscle cells.
Next, the scientists created mice that were genetically engineered to over-express the protein in
their vascular smooth muscle cells.
The postnatal adipose tissue contains a heterogeneous population of cells which includes adult stem cells (i.e., MSCs), endothelial progenitor cells, leukocytes, endothelial cells, and
vascular smooth muscle cells.
The post holder will perform research investigating the role of exosomes in
vascular smooth muscle cell (VSMC) biology.
Chairs: Rama Natarajan, Beckman Research Institute of City of Hope and Marianne Grant, Beth Israel Deaconess Medical Center Philip Marsden, University of Toronto Epigenetic regulation of endothelial phenotype: the role of the non coding genome Kathleen Martin, Yale School of Medicine Transcriptional and epigenetic regulation in vascular smooth muscle cells
The team identified the connections between rs9349379 and EDN1 by deleting a region of DNA at the SNP in human pluripotent stem cells and then converting these immature cells into endothelial cells and
vascular smooth muscle cells.
EDR activity involves the release of endothelial nitric oxide (NO) release and subsequent increase in cyclic guanosine monophosphate (GMP) levels in
the vascular smooth muscle cells ultimately increasing vasodilation and blood flow.