At present, the precise mechanisms underlying the rapid alterations
in vascular tone remain to be resolved.
Interestingly, as many as nine of the genes have been previously associated with some vascular disease and four more are known to be involved in the regulation
of vascular tone, supporting the importance of blood vessels in migraine attacks.
Warm water compresses can increase the amount of breast milk by
improving vascular tone, and by preventing the stasis of milk, which helps in milk let down.
Calcium is the most abundant mineral in the body, required
for vascular tone, muscle function, nerve transmission, and hormone secretion.
Estrogen dominance is known to cause vascular dilation, while progesterone restores
normal vascular tone.
Mechanical influences on skeletal
muscle vascular tone in humans: insight into contraction - induced rapid vasodilatation.
The reason for this is that moist heat increases circulation and
improves vascular tone (meaning it allows the milk ducts to open rather than constrict).
In cerebral vascular smooth muscle cells, cannabinoid - induced inhibition of voltage-gated Ca (2 +) channels leads to vasodilation and
decreased vascular tone (By similarity).
Potassium channels help maintain
the vascular tone of the pulmonary artery and help it respond to low levels of oxygen.
It is interesting that the balance of redox modulation of
vascular tone, imposed by the O2 • −: NO ratio, may be tipped in either direction to promote disequilibrium, as maternal treatment with vitamin C in normoxic pregnancy also promoted endothelial dysfunction.
It restores proper cellular oxygen levels, improves
vascular tone, normalizes blood clotting, and prevents cyclical migraines and arterial plaque.
Vascular tone, how much the blood vessels are constricted in increased by insulin by increased intracellular calcium and activation of the sympathetic nervous system.
«Arginine serves as a dietary precursor for the formation of nitric oxide, a potent mediator of
vascular tone and, therefore, may have implications for the health of the cardiovascular system.
Kar P, Laight D, Rooprai HK, Shaw KM, Cummings M. Effects of grape seed extract in Type 2 diabetic subjects at high cardiovascular risk: a double blind randomized placebo controlled trial examining metabolic markers,
vascular tone, inflammation, oxidative stress and insulin sensitivity.
In turn, nitric oxide bioavailability deeply influences insulin - stimulated glucose uptake and
vascular tone.
Diabetic Medicine, May 2009, 26 (5): 526ï ¿ 1/2 531, «Effects of grape seed extract in Type 2 diabetic subjects at high cardiovascular risk: a double blind randomized placebo controlled trial examining metabolic markers,
vascular tone, inflammation, oxidative stress and insulin sensitivity»