A. Mansour et al., «An in vivo model of functional and
vascularized human brain organoids,» Nat Biotechnol, doi: 10.1038 / nbt.4127, 2018.
Tissue engineers have tried for years to produce lab - grown
vascularized human tissues robust enough to serve as replacements for damaged human tissue.
Not exact matches
Using the TEER - MEA chip, the researchers built a beating
vascularized Heart Chip in which
human cardiomyocytes are cultured in one microfluidic channel that is separated by a thin semi-permeable membrane from a second, parallel endothelium - lined vascular channel.
Generation of a
vascularized and functional
human liver from an iPSC - derived organ bud transplant.
Researchers from the laboratories of Hiroshi Y. Yoshikawa and Hideki Taniguchi had previously demonstrated the in vitro formation of a 3D transplantable liver «organ bud» from
human induced pluripotent stem cells (iPSCs) co-cultured with mesenchymal and endothelial progenitors, and allows for the growth of a small
vascularized and functional organ [1 - 3].
A team at the Harvard John A. Paulson School for Engineering and Applied Sciences (SEAS) and the Wyss Institute for Biologically Inspired Engineering at Harvard University has invented a method for 3D bioprinting thick
vascularized tissue constructs composed of
human stem cells, extracellular matrix, and circulatory channels lined with endothelial blood vessel cells.